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Gtf3c3 general transcription factor IIIC, polypeptide 3 [ Mus musculus (house mouse) ]

Gene ID: 98488, updated on 18-Sep-2024

Summary

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Official Symbol
Gtf3c3provided by MGI
Official Full Name
general transcription factor IIIC, polypeptide 3provided by MGI
Primary source
MGI:MGI:2138383
See related
Ensembl:ENSMUSG00000041303 AllianceGenome:MGI:2138383
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TFIIIC102; TF3C-gamma
Summary
Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Predicted to be part of transcription factor TFIIIC complex. Is expressed in testis. Orthologous to human GTF3C3 (general transcription factor IIIC subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 7.2), CNS E18 (RPKM 5.0) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Gtf3c3 in Genome Data Viewer
Location:
1 C1.2; 1 27.13 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (54435036..54478185, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (54395877..54439026, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51622 Neighboring gene STARR-seq mESC enhancer starr_00932 Neighboring gene predicted gene, 25829 Neighboring gene coiled-coil domain containing 150 Neighboring gene STARR-seq mESC enhancer starr_00933 Neighboring gene STARR-seq mESC enhancer starr_00934 Neighboring gene STARR-seq mESC enhancer starr_00935 Neighboring gene predicted gene, 34066 Neighboring gene STARR-seq mESC enhancer starr_00936 Neighboring gene post-GPI attachment to proteins 1 Neighboring gene predicted gene, 51623

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. Moniot B, et al. Development, 2014 Sep. PMID 25142465
  2. Systematic identification of factors for provirus silencing in embryonic stem cells. Yang BX, et al. Cell, 2015 Sep 24. PMID 26365490, Free PMC Article
  3. Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. Barnes CE, et al. Mol Omics, 2022 Jan 17. PMID 34709266, Free PMC Article
  4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
  5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
part_of transcription factor TFIIIC complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIIIC complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
general transcription factor 3C polypeptide 3
Names
TFIIIC 102 kDa subunit
transcription factor IIIC-gamma subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033194.3 → NP_001028366.1  general transcription factor 3C polypeptide 3

    See identical proteins and their annotated locations for NP_001028366.1

    Status: VALIDATED

    Source sequence(s)
    AC124538, BC141157, BY272879
    Consensus CDS
    CCDS14958.1
    UniProtKB/TrEMBL
    Q3TMP1
    Related
    ENSMUSP00000039420.7, ENSMUST00000041638.8
    Conserved Domains (3) summary
    sd00006
    Location:179 → 207
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:212 → 276
    TPR_11; TPR repeat
    pfam13432
    Location:421 → 485
    TPR_16; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    54435036..54478185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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