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ubiX flavin prenyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949033, updated on 10-Oct-2024

Summary

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Official Symbol
ubiX
Official Full Name
flavin prenyltransferase
Primary source
ECOCYC:EG11044
Locus tag
b2311
See related
ASAP:ABE-0007628
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dedF; ECK2305
Summary
Genetic interactions between ubiX and ubiG as well as their mutant phenotypes indicate that UbiX and UbiG must interact to be able to carry out the 3-octaprenyl-4-hydroxybenzoate decarboxylase step in ubiquinone biosynthesis during logarithmic growth. [More information is available at EcoCyc: EG11044].
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Genomic context

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Sequence:
NC_000913.3 (2428057..2428626, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene histidine ABC transporter periplasmic binding protein Neighboring gene lysine/arginine/ornithine ABC transporter periplasmic binding protein Neighboring gene amidophosphoribosyltransferase Neighboring gene colicin V production protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in prokaryotic cells. Park KS, et al. J Bacteriol, 2005 Aug. PMID 16030245, Free PMC Article
  2. Regulation of Escherichia coli purF. Analysis of the control region of a pur regulon gene. Makaroff CA, et al. J Biol Chem, 1985 Aug 25. PMID 2991286
  3. Low ubiquinone content in Escherichia coli causes thiol hypersensitivity. Zeng H, et al. J Bacteriol, 1998 Jul. PMID 9658014, Free PMC Article
  4. Genetic evidence for an interaction of the UbiG O-methyltransferase with UbiX in Escherichia coli coenzyme Q biosynthesis. Gulmezian M, et al. J Bacteriol, 2006 Sep. PMID 16923914, Free PMC Article
  5. Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase. Lin F, et al. ACS Chem Biol, 2015 Apr 17. PMID 25647642

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carboxy-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables flavin prenyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables flavin prenyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables flavin prenyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables prenyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in prenyl-FMNH2 biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ubiquinone biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ubiquinone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
flavin prenyltransferase
NP_416814.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2428057..2428626 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416814.1 flavin prenyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416814.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN3WHG5
    Conserved Domains (1) summary
    PRK06029
    Location:1 → 187
    PRK06029; UbiX family flavin prenyltransferase
Nucleotide Protein
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