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clsC cardiolipin synthase C [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947321, updated on 10-Oct-2024

Summary

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Official Symbol
clsC
Official Full Name
cardiolipin synthase C
Primary source
ECOCYC:G6551
Locus tag
b1046
See related
ASAP:ABE-0003551
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1032; ymdC
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Genomic context

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Sequence:
NC_000913.3 (1106355..1107776)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YmdA Neighboring gene 2'-O-acetyl-ADP-ribose deacetylase, regulator of RNase III activity Neighboring gene osmoregulated periplasmic glucans (OPG) biosynthesis protein C Neighboring gene osmoregulated periplasmic glucans biosynthesis protein G Neighboring gene osmoregulated periplasmic glucans biosynthesis protein H

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A second Escherichia coli protein with CL synthase activity. Guo D, et al. Biochim Biophys Acta, 2000 Jan 17. PMID 10634942
  2. Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates. Tan BK, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 22988102, Free PMC Article
  3. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article
  4. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article
  5. The complete genome sequence of Escherichia coli K-12. Blattner FR, et al. Science, 1997 Sep 5. PMID 9278503

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The unusual substrate specificity of Escherichia coli cardiolipin synthase C does not require the product of the transcriptionally engaged ymdB gene.
    Title: The unusual substrate specificity of Escherichia coli cardiolipin synthase C does not require the product of the transcriptionally engaged ymdB gene.
  2. Data indicate that the cardiolipin synthase DeltaclsABC mutant (clsA, clsB(ybhO) and clsC (ymdC))nlacks detectible cardiolipin (CL) regardless of growth phase or growth conditions.
    Title: Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphotransferase activity, for other substituted phosphate groups IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cardiolipin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cardiolipin biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cardiolipin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cardiolipin synthase C
NP_415564.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1106355..1107776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415564.2 cardiolipin synthase C [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415564.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0B0W257, A0A1E5M7Y4, A0A836NEV2, A0AAD0K7G6, A0AAN3P6T9, B7NAS1
    Conserved Domains (2) summary
    cd09111
    Location:24 → 184
    PLDc_ymdC_like_1; Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins
    cd09113
    Location:250 → 469
    PLDc_ymdC_like_2; Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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