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psuG pseudouridine-5'-phosphate glycosidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946699, updated on 19-Sep-2024

Summary

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Official Symbol
psuG
Official Full Name
pseudouridine-5'-phosphate glycosidase
Primary source
ECOCYC:EG12033
Locus tag
b2165
See related
ASAP:ABE-0007165
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2158; pscG; yeiN
Summary
PsuG was characterized in Escherichia coli UT189 (Preumont, 2008). [More information is available at EcoGene: EG12033]. YeiN from the uropathogenic Escherichia coli UTI89 is a pseudouridine 5'-phosphate glycosidase . [More information is available at EcoCyc: EG12033].
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Genomic context

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Sequence:
NC_000913.3 (2257429..2258367, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator YeiL Neighboring gene putative pseudouridine transporter Neighboring gene putative pseudouridine kinase Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruA Neighboring gene 1-phosphofructokinase Neighboring gene fructose-specific PTS multiphosphoryl transfer protein FruB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pseudouridylate synthetase of Escherichia coli: a catabolite-repressible enzyme. Solomon LR, et al. J Bacteriol, 1971 Aug. PMID 4329733, Free PMC Article
  2. Pseudouridulate synthetase of Escherichia coli: correlation of its activity with utilization of pseudouridine for growth. Breitman TR. J Bacteriol, 1970 Jul. PMID 4912525, Free PMC Article
  3. Growth of pyrimidineless strains of Escherichia coli on 5-ribosyluracil (pseudouridine). Breitman TR, et al. J Bacteriol, 1968 Nov. PMID 4882030, Free PMC Article
  4. The biosynthesis of pseudouridine in ribonucleic acids of Escherichia coli. Ginsberg T, et al. J Biol Chem, 1968 Dec 10. PMID 4881361
  5. Pseudouridine monophosphate glycosidase: a new glycosidase mechanism. Huang S, et al. Biochemistry, 2012 Nov 13. PMID 23066817, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydrolase activity, acting on glycosyl bonds IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables manganese ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pseudouridylate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pseudouridylate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pseudouridylate synthase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in nucleobase catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
pseudouridine-5'-phosphate glycosidase
NP_416670.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2257429..2258367 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416670.1 pseudouridine-5'-phosphate glycosidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416670.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EDH1
    Conserved Domains (1) summary
    COG2313
    Location:1 → 311
    PsuG; Pseudouridine-5'-phosphate glycosidase (pseudoU degradation) [Nucleotide transport and metabolism]
Nucleotide Protein
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