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wcaB colanic acid biosynthesis acetyltransferase WcaB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946573, updated on 19-Sep-2024

Summary

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Official Symbol
wcaB
Official Full Name
colanic acid biosynthesis acetyltransferase WcaB
Primary source
ECOCYC:G7103
Locus tag
b2058
See related
ASAP:ABE-0006813
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2052
Summary
WcaB contains hexapeptide repeats. [More information is available at EcoGene: EG13570]. WcaB is believed to be an acetyl transferase involved in colanic acid synthesis based on sequence similarity and its presence in a putative colanic acid synthesis operon . wcaB was shown to not be expressed when cultured in rich medium . wcaB was shown to be upregulated in response to osmotic shock and in sessile bacteria . [More information is available at EcoCyc: G7103].
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Genomic context

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Sequence:
NC_000913.3 (2132067..2132555, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene GDP-Fuc:2/3-O-Ac-alpha-L-Fuc-(1->3)-alpha-D-Glc-PP-Und alpha-(1,4)-fucosyltransferase Neighboring gene colanic acid polymerase Neighboring gene colanic acid biosynthesis galactosyltransferase WcaC Neighboring gene UDP-glucuronate:2-O-Ac-beta-D-Gal-(1->3)-alpha-L-Fuc-(1->4)-2/3-O-Ac-alpha-L-Fuc-(1->3)-beta-D-Glc-PP-Und beta-(1,3)-glucuronosyltransferase Neighboring gene protein-tyrosine kinase Wzc

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables O-acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables acetyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
  
enables serine O-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within colanic acid biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within colanic acid biosynthetic process IGC
Inferred from Genomic Context
more info
 PubMed 
involved_in cysteine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
  
involved_in lipopolysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in slime layer polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
colanic acid biosynthesis acetyltransferase WcaB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2132067..2132555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416562.1 colanic acid biosynthesis acetyltransferase WcaB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416562.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376M5X1
    Conserved Domains (1) summary
    PRK10191
    Location:17 → 162
    PRK10191; putative acyl transferase; Provisional
Nucleotide Protein
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