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osmC osmotically inducible peroxiredoxin OsmC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946043, updated on 19-Sep-2024

Summary

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Official Symbol
osmC
Official Full Name
osmotically inducible peroxiredoxin OsmC
Primary source
ECOCYC:EG10680
Locus tag
b1482
See related
ASAP:ABE-0004944
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1476
Summary
OsmC contains a conserved CxxS redox motif. [More information is available at EcoGene: EG10680]. OsmC is a non-essential protein which has been shown to have peroxidase activity with a strong preference for organic hydroperoxide . [More information is available at EcoCyc: EG10680].
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Genomic context

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Sequence:
NC_000913.3 (1556625..1557056)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ribosome-associated protein Sra Neighboring gene biofilm-dependent modulation protein Neighboring gene putative D,D-dipeptide ABC transporter ATP-binding subunit DdpF Neighboring gene putative D,D-dipeptide ABC transporter ATP-binding subunit DdpD Neighboring gene putative D,D-dipeptide ABC transporter membrane subunit DdpC Neighboring gene putative D,D-dipeptide ABC transporter membrane subunit DdpB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Osmotic induction of gene osmC expression in Escherichia coli K12. Gutierrez C, et al. J Mol Biol, 1991 Aug 20. PMID 1715407
  2. Growth-phase-dependent expression of the osmotically inducible gene osmC of Escherichia coli K-12. Gordia S, et al. Mol Microbiol, 1996 Feb. PMID 8820643
  3. Structure of OsmC from Escherichia coli: a salt-shock-induced protein. Shin DH, et al. Acta Crystallogr D Biol Crystallogr, 2004 May. PMID 15103136
  4. Crystallographic structure and biochemical analysis of the Thermus thermophilus osmotically inducible protein C. Rehse PH, et al. J Mol Biol, 2004 May 14. PMID 15111059
  5. Interplay between global regulators of Escherichia coli: effect of RpoS, Lrp and H-NS on transcription of the gene osmC. Bouvier J, et al. Mol Microbiol, 1998 Jun. PMID 9663683

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
  2. The crystal structure of an osmotically inducible protein (OsmC) from Escherichia coli has been determined
    Title: Structure of OsmC from Escherichia coli: a salt-shock-induced protein.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables peroxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables peroxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables peroxiredoxin activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within hyperosmotic response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to hydroperoxide IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
osmotically inducible peroxiredoxin OsmC
NP_415999.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1556625..1557056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415999.1 osmotically inducible peroxiredoxin OsmC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415999.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAI9FGG9
    Conserved Domains (1) summary
    TIGR03562
    Location:5 → 138
    osmo_induc_OsmC; peroxiredoxin, OsmC subfamily
Nucleotide Protein
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