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nth endonuclease III, apurinic apyrimidic DNA lyase [ Bacillus subtilis subsp. subtilis str. 168 ]

Gene ID: 939036, updated on 6-Aug-2024

Summary

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Gene symbol
nth
Gene description
endonuclease III, apurinic apyrimidic DNA lyase
Locus tag
BSU_22340
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
Lineage
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
Old locus tag
BSU22340
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Genomic context

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Sequence:
NC_000964.3 (2344755..2345414, complement)

NC_000964.3Genomic Context describing neighboring genes Neighboring gene Holliday junction resolvase Neighboring gene peptidoglycan glycosyltransferase (penicillin-binding proteins 1A and 1B) Neighboring gene hypothetical protein Neighboring gene DNA-remodelling primosomal protein Neighboring gene asparaginyl-tRNA synthetase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000964.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites. Collier C, et al. Nucleic Acids Res, 2012 Jan. PMID 21954439, Free PMC Article
  2. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
  3. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
  4. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article
  5. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Kunst F, et al. Nature, 1997 Nov 20. PMID 9384377

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nucleoid associated proteins with DNA untwisting activities facilitate Nth-mediated base excision repair.
    Title: Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
endonuclease III, apurinic apyrimidic DNA lyase
NP_390115.1
  • Evidence 1a: Function from experimental evidences in the studied strain; PubMedId: 9808040, 11160880, 12682299, 21954439, 24914186; Product type e: enzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000964.3 Reference assembly

    Range
    2344755..2345414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_390115.1 endonuclease III, apurinic apyrimidic DNA lyase [Bacillus subtilis subsp. subtilis str. 168]

    See identical proteins and their annotated locations for NP_390115.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    D4FY00
    Conserved Domains (2) summary
    smart00525
    Location:188 → 206
    FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
    TIGR01083
    Location:5 → 196
    nth; endonuclease III
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39788.1

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases