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pucL factor-independent urate hydroxylase [ Haloferax volcanii DS2 ]

Gene ID: 8919178, updated on 22-Oct-2024

Summary

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Gene symbol
pucL
Gene description
factor-independent urate hydroxylase
Locus tag
HVO_RS01450
Gene type
protein coding
Organism
Haloferax volcanii DS2 (strain: DS2, type-material: type strain of Halobacterium volcanii)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group; Halobacteria; Halobacteriales; Haloferacaceae; Haloferax
Old locus tag
HVO_B0300
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Genomic context

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Location:
plasmid: pHV3
Sequence:
NC_013964.1 (346679..347665, complement)

NC_013964.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hydroxyisourate hydrolase Neighboring gene 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase Neighboring gene dihydroorotase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_013964.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Bui S, et al. Angew Chem Int Ed Engl, 2014 Dec 8. PMID 25314114, Free PMC Article
  2. Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution. Colloc'h N, et al. Nat Struct Biol, 1997 Nov. PMID 9360612
  3. The complete genome sequence of Haloferax volcanii DS2, a model archaeon. Hartman AL, et al. PLoS One, 2010 Mar 19. PMID 20333302, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
factor-independent urate hydroxylase
WP_004041240.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_013964.1 Reference assembly

    Range
    346679..347665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004041240.1 factor-independent urate hydroxylase [Haloferax volcanii]

    See identical proteins and their annotated locations for WP_004041240.1

    UniProtKB/TrEMBL
    A0A8T5CIU9, L9VIK9, M0IIK5
    Conserved Domains (2) summary
    COG3648
    Location:17 → 324
    UriC; Uricase (urate oxidase) [Secondary metabolites biosynthesis, transport and catabolism]
    cl00263
    Location:22 → 322
    TFold; Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl ...
Nucleotide Protein
Heading Accession and Version

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