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gmhA phosphoheptose isomerase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886905, updated on 6-Aug-2024

Summary

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Gene symbol
gmhA
Gene description
phosphoheptose isomerase
Locus tag
Rv0113
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
lpcA
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Genomic context

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Sequence:
NC_000962.3 (137319..137909)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene acyltransferase Neighboring gene GDP-mannose 4,6-dehydratase Neighboring gene D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase Neighboring gene D-alpha-D-heptose-7-phosphate kinase HddA Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway. Karan S, et al. Sci Rep, 2020 Nov 30. PMID 33257730, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway.
    Title: Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway.
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General gene information

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Homology

General protein information

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Preferred Names
phosphoheptose isomerase
NP_214627.1
  • sedoheptulose-7-phosphate isomerase GmhA. Belongs to the sis family, LPCA subfamily. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007 PMID:17545187).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    137319..137909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_214627.1 phosphoheptose isomerase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_214627.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0E7ZI65
    Conserved Domains (1) summary
    cl00389
    Location:1 → 196
    SIS; SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WGG1.1

Gene LinkOut

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