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trxB2 thioredoxin reductase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886232, updated on 4-Apr-2024

Summary

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Gene symbol
trxB2
Gene description
thioredoxin reductase
Locus tag
Rv3913
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
trxR
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Genomic context

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Sequence:
NC_000962.3 (4401728..4402735)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene ECF RNA polymerase sigma factor SigM Neighboring gene anti-sigma-M factor RsmA Neighboring gene thioredoxin TrxC Neighboring gene peptidoglycan hydrolase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense. Lin K, et al. PLoS Pathog, 2016 Jun. PMID 27249779, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These studies reveal TrxB2 as essential thiol-reducing enzyme in Mycobacterium tuberculosis in vitro and during infection
    Title: Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
thioredoxin reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4401728..4402735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218430.1 thioredoxin reductase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218430.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654T751
    Conserved Domains (1) summary
    TIGR01292
    Location:16 → 315
    TRX_reduct; thioredoxin-disulfide reductase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WHH1.1

Gene LinkOut

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