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mvfR transcriptional regulator MvfR [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879994, updated on 24-Aug-2024

Summary

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Gene symbol
mvfR
Gene description
transcriptional regulator MvfR
Locus tag
PA1003
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (1086097..1087095, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene 3-oxoacyl-ACP synthase Neighboring gene thioesterase PqsE Neighboring gene anthranilate synthase component I Neighboring gene anthranilate synthase component II Neighboring gene quinolinate synthetase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pharmacological Inhibition of the Pseudomonas aeruginosa MvfR Quorum-Sensing System Interferes with Biofilm Formation and Potentiates Antibiotic-Mediated Biofilm Disruption. Maura D, et al. Antimicrob Agents Chemother, 2017 Dec. PMID 28923875, Free PMC Article
  2. Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa. Zaborina O, et al. PLoS Pathog, 2007 Mar. PMID 17367209, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pharmacological inhibition of the P. aeruginosa quorum-sensing regulator MvfR (PqsR) interferes with biofilm formation and potentiates biofilm sensitivity to antibiotics.
    Title: Pharmacological Inhibition of the Pseudomonas aeruginosa MvfR Quorum-Sensing System Interferes with Biofilm Formation and Potentiates Antibiotic-Mediated Biofilm Disruption.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of lyase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
transcriptional regulator MvfR
NP_249694.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    1086097..1087095 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_249694.1 transcriptional regulator MvfR [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_249694.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A367M3Q2, A0A7G9KWC2
    Conserved Domains (1) summary
    COG0583
    Location:4 → 297
    LysR; DNA-binding transcriptional regulator, LysR family [Transcription]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I4X0.1

Gene LinkOut

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Molecular Biology Databases
Research Materials