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fimX protein FimX [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 878416, updated on 24-Aug-2024

Summary

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Gene symbol
fimX
Gene description
protein FimX
Locus tag
PA4959
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (5565493..5567568)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene phosphatidylserine decarboxylase Neighboring gene cyclic-di-GMP receptor FimW Neighboring gene phosphoserine phosphatase Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of an EAL domain in complex with reaction product 5'-pGpG. Robert-Paganin J, et al. PLoS One, 2012. PMID 23285035, Free PMC Article
  2. Interaction of the cyclic-di-GMP binding protein FimX and the Type 4 pilus assembly ATPase promotes pilus assembly. Jain R, et al. PLoS Pathog, 2017 Aug. PMID 28854278, Free PMC Article
  3. Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX. Navarro MV, et al. Structure, 2009 Aug 12. PMID 19679088, Free PMC Article
  4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. FimX can promote Type IVa pili assembly when intracellular levels of this cyclic nucleotide are low
    Title: Interaction of the cyclic-di-GMP binding protein FimX and the Type 4 pilus assembly ATPase promotes pilus assembly.
  2. Two crystallographic structures of the EAL domain of FimX (residues 438-686): one of the apo form and the other of a complex with 5'-pGpG, are reported.
    Title: Crystal structure of an EAL domain in complex with reaction product 5'-pGpG.
  3. Data from crystallographic EAL domain dimer suggests modes for the regulation of FimX by c-di-GMP binding.
    Title: Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX.
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General gene information

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Homology

General protein information

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Preferred Names
protein FimX
NP_253646.1
  • class 1: Function experimentally demonstrated in P. aeruginosa

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    5565493..5567568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_253646.1 protein FimX [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_253646.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5DLC9
    Conserved Domains (3) summary
    PRK09776
    Location:145 → 683
    PRK09776; putative diguanylate cyclase; Provisional
    cd00156
    Location:11 → 105
    REC; phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs)
    pfam00563
    Location:444 → 678
    EAL; EAL domain
Nucleotide Protein
Heading Accession and Version

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