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pyrE orotate phosphoribosyltransferase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 878227, updated on 24-Sep-2023

Summary

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Gene symbol
pyrE
Gene description
orotate phosphoribosyltransferase
Locus tag
PA5331
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (6001399..6002040, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene mono-heme cytochrome C Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene catabolite repression control protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  2. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  3. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  4. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article
  5. Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Filiatrault MJ, et al. Infect Immun, 2005 Jun. PMID 15908409, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables orotate phosphoribosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables orotate phosphoribosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within pyrimidine nucleotide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pyrimidine nucleotide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
orotate phosphoribosyltransferase
NP_254018.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    6001399..6002040 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_254018.1 orotate phosphoribosyltransferase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_254018.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P50587
    Conserved Domains (1) summary
    PRK00455
    Location:1 → 213
    pyrE; orotate phosphoribosyltransferase; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50587.2

Gene LinkOut

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Molecular Biology Databases
Research Materials