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ppx exopolyphosphatase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 877947, updated on 11-Sep-2024

Summary

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Gene symbol
ppx
Gene description
exopolyphosphatase
Locus tag
PA5241
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (5900879..5902399)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene transcription termination factor Rho Neighboring gene thioredoxin Neighboring gene polyphosphate kinase Neighboring gene delta-aminolevulinic acid dehydratase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Exopolyphosphatase of Pseudomonas aeruginosa is essential for the production of virulence factors, and its expression is controlled by NtrC and PhoB acting at two interspaced promoters. Gallarato LA, et al. Microbiology (Reading), 2014 Feb. PMID 24275100
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Under nitrogen-limiting conditions, expression of ppx was controlled from a sigma(54)-dependent promoter activated by the response regulator NtrC, while under Pi limitation, the expression was controlled from a sigma(70) promoter, activated by PhoB.
    Title: Exopolyphosphatase of Pseudomonas aeruginosa is essential for the production of virulence factors, and its expression is controlled by NtrC and PhoB acting at two interspaced promoters.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables exopolyphosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within bacterial-type flagellum-dependent swarming motility IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within bacterial-type flagellum-dependent swimming motility IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cellular response to nitrogen starvation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within cellular response to phosphate starvation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within glycolipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within quorum sensing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within single-species biofilm formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
exopolyphosphatase
NP_253928.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    5900879..5902399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_253928.1 exopolyphosphatase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_253928.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9S605, Q9S647
    UniProtKB/TrEMBL
    A0A0H2ZJ54, A0A1X0SUB8
    Conserved Domains (1) summary
    COG0248
    Location:13 → 499
    GppA; Exopolyphosphatase/pppGpp-phosphohydrolase [Nucleotide transport and metabolism, Signal transduction mechanisms, Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZN70.1

Gene LinkOut

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Molecular Biology Databases
Research Materials