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topA DNA topoisomerase I [ Methanobrevibacter ruminantium M1 ]

Gene ID: 8770031, updated on 22-Oct-2024

Summary

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Gene symbol
topA
Gene description
DNA topoisomerase I
Locus tag
MRU_RS01990
Gene type
protein coding
Organism
Methanobrevibacter ruminantium M1 (strain: M1, culture-collection: DSM:1093, type-material: type strain of Methanobrevibacter ruminantium)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Methanomada group; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanobrevibacter
Old locus tag
mru_0390
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Genomic context

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Sequence:
NC_013790.1 (557952..560177)

NC_013790.1Genomic Context describing neighboring genes Neighboring gene phosphoserine phosphatase SerB Neighboring gene hypothetical protein Neighboring gene STT3 domain-containing protein Neighboring gene GTP-binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_013790.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions. Leahy SC, et al. PLoS One, 2010 Jan 28. PMID 20126622, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
DNA topoisomerase I
WP_012955193.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_013790.1 Reference assembly

    Range
    557952..560177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_012955193.1 DNA topoisomerase I [Methanobrevibacter ruminantium]

    See identical proteins and their annotated locations for WP_012955193.1

    UniProtKB/TrEMBL
    D3E0J6
    Conserved Domains (6) summary
    cd03362
    Location:4 → 151
    TOPRIM_TopoIA_TopoIII; TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving ...
    COG0551
    Location:587 → 705
    YrdD; ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1 [Replication, recombination and repair]
    cd00186
    Location:159 → 564
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
    TIGR01057
    Location:6 → 618
    topA_arch; DNA topoisomerase I, archaeal
    pfam01396
    Location:675 → 711
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger
    cl00713
    Location:624 → 657
    Auto_anti-p27; Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
Nucleotide Protein
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