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scrA hypothetical protein [ Dictyostelium discoideum AX4 ]

Gene ID: 8625028, updated on 18-Sep-2024

Summary

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Official Symbol
scrA
Official Full Name
hypothetical protein
Primary source
dictyBase:DDB_G0285253
Locus tag
DDB_G0285253
See related
AmoebaDB:DDB_G0285253; VEuPathDB:DDB_G0285253
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium
Old locus tag
DDBDRAFT_0186429; DDBDRAFT_0191148; DDB_0186429; DDB_0191148
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Genomic context

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Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_007090.3 (3055336..3056667)

Chromosome 4 - NC_007090.3Genomic Context describing neighboring genes Neighboring gene RhoGEF domain-containing protein Neighboring gene hypothetical protein Neighboring gene tRNA-Asp Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007090.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A plasma membrane template for macropinocytic cups. Veltman DM, et al. Elife, 2016 Dec 13. PMID 27960076, Free PMC Article
  2. Abi mutants in Dictyostelium reveal specific roles for the SCAR/WAVE complex in cytokinesis. Pollitt AY, et al. Curr Biol, 2008 Feb 12. PMID 18261908
  3. Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis. Yang Y, et al. J Cell Biol, 2021 Jul 5. PMID 33978708, Free PMC Article
  4. WASP family proteins and formins compete in pseudopod- and bleb-based migration. Davidson AJ, et al. J Cell Biol, 2018 Feb 5. PMID 29191847, Free PMC Article
  5. The WASp-like protein scar regulates macropinocytosis, phagocytosis and endosomal membrane flow in Dictyostelium. Seastone DJ, et al. J Cell Sci, 2001 Jul. PMID 11683394

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables Arp2/3 complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase A regulatory subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled chemorepellent receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within bleb assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within bleb assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cell-substrate adhesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within chemotaxis to cAMP IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within exocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within late endosome to lysosome transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within macropinocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitotic spindle organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phagocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pinocytosis TAS
Traceable Author Statement
more info
 PubMed 
involved_in positive regulation of Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pseudopodium assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in pseudopodium assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of actin polymerization or depolymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sorocarp morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SCAR complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SCAR complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in actin cytoskeleton TAS
Traceable Author Statement
more info
 PubMed 
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell leading edge IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell leading edge IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in cell pole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cell-cell junction IC
Inferred by Curator
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
 PubMed 
located_in filopodium tip IC
Inferred by Curator
more info
 PubMed 
located_in filopodium tip IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with macropinocytic cup IDA
Inferred from Direct Assay
more info
 PubMed 
located_in pseudopodium IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ruffle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
hypothetical protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007090.3 Reference assembly

    Range
    3055336..3056667
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_633219.1 → XP_638311.1  hypothetical protein DDB_G0285253 [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_638311.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q54NF8, Q9XYA8
Nucleotide Protein
Heading Accession and Version

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