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guaB [ Dictyostelium discoideum AX4 ]

Gene ID: 8624219, updated on 22-Aug-2024

Summary

Official Symbol
guaB
Primary source
dictyBase:DDB_G0283701
Locus tag
DDB_G0283701
See related
AmoebaDB:DDB_G0283701; VEuPathDB:DDB_G0283701
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium
Old locus tag
DDBDRAFT_0185636; DDBDRAFT_0230098; DDB_0185636; DDB_0230098
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Genomic context

Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_007090.3 (1000722..1002269, complement)

Chromosome 4 - NC_007090.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ARK family protein kinase Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Pathways from PubChem

General protein information

Preferred Names
IMP dehydrogenase
Names
inosine-5'-monophosphate dehydrogenase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007090.3 Reference assembly

    Range
    1000722..1002269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_633881.1XP_638973.1  IMP dehydrogenase [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_638973.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q54QQ0
    Conserved Domains (3) summary
    cd00381
    Location:35494
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
    cd04602
    Location:121232
    CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
    PTZ00314
    Location:20511
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional