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calA hypothetical protein [ Dictyostelium discoideum AX4 ]

Gene ID: 8622104, updated on 18-Sep-2024

Summary

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Official Symbol
calA
Official Full Name
hypothetical protein
Primary source
dictyBase:DDB_G0279407
Locus tag
DDB_G0279407
See related
AmoebaDB:DDB_G0279407; VEuPathDB:DDB_G0279407
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium
Old locus tag
DDBDRAFT_0205842; DDBDRAFT_0214955; DDB_0205842; DDB_0214955
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Genomic context

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Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_007089.4 (2244074..2245039, complement)

Chromosome 3 - NC_007089.4Genomic Context describing neighboring genes Neighboring gene RNA recognition motif-containing protein RRM Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transmembrane protein 184C

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007089.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer. O'Day DH, et al. Int J Mol Sci, 2020 Feb 11. PMID 32054133, Free PMC Article
  2. Inducible expression of calmodulin antisense RNA in Dictyostelium cells inhibits the completion of cytokinesis. Liu T, et al. Mol Biol Cell, 1992 Dec. PMID 1493336, Free PMC Article
  3. Association of calmodulin and an unconventional myosin with the contractile vacuole complex of Dictyostelium discoideum. Zhu Q, et al. J Cell Biol, 1992 Jul. PMID 1629238, Free PMC Article
  4. Structural and functional properties of calmodulin from the eukaryotic microorganism Dictyostelium discoideum. Marshak DR, et al. Biochemistry, 1984 Jun 19. PMID 6087882
  5. Isolation and properties of calmodulin from Dictyostelium discoideum. Clarke M, et al. J Bacteriol, 1980 Jan. PMID 6243626, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer.
    Title: Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cell adhesion molecule binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cyclic nucleotide phosphodiesterase activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cyclic-nucleotide phosphodiesterase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables enzyme regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables myosin I binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables troponin I binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in establishment of protein localization to vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of asexual reproduction IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of proteolysis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in plasma membrane repair IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of positive chemotaxis to cAMP IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of sequestering of calcium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein export from nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of sorocarp stalk cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in contractile vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in contractile vacuole IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular matrix IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hypothetical protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007089.4 Reference assembly

    Range
    2244074..2245039 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_636603.1 → XP_641695.1  hypothetical protein DDB_G0279407 [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_641695.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P02599, Q54WM2
    Conserved Domains (2) summary
    PTZ00184
    Location:3 → 151
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:87 → 148
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

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