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dstB signal transducer and activator of transcription family protein [ Dictyostelium discoideum AX4 ]

Gene ID: 8616516, updated on 18-Sep-2024

Summary

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Official Symbol
dstB
Official Full Name
signal transducer and activator of transcription family protein
Primary source
dictyBase:DDB_G0268638
Locus tag
DDB_G0268638
See related
AmoebaDB:DDB_G0268638; VEuPathDB:DDB_G0268638
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium
Old locus tag
DDBDRAFT_0189921; DDBDRAFT_0191116; DDB_0189921; DDB_0191116
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Genomic context

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Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_007087.3 (1834587..1838131, complement)

Chromosome 1 - NC_007087.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene 3',5'-bisphosphate nucleotidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007087.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development. Zhukovskaya NV, et al. Development, 2004 Jan. PMID 14701681
  2. The genome of the social amoeba Dictyostelium discoideum. Eichinger L, et al. Nature, 2005 May 5. PMID 15875012, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in defense response IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
signal transducer and activator of transcription family protein
XP_646834.1
  • Similar to STAT

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007087.3 Reference assembly

    Range
    1834587..1838131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_641742.1 → XP_646834.1  signal transducer and activator of transcription family protein [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_646834.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q55F36, Q70GP4
    Conserved Domains (2) summary
    cd09919
    Location:981 → 1132
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    pfam09267
    Location:654 → 767
    Dict-STAT-coil; Dictyostelium STAT, coiled coil
Nucleotide Protein
Heading Accession and Version

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