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RTC3 Rtc3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856487, updated on 18-Sep-2024

Summary

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Official Symbol
RTC3
Official Full Name
Rtc3p
Primary source
SGD:S000001129
Locus tag
YHR087W
See related
AllianceGenome:SGD:S000001129; FungiDB:YHR087W; VEuPathDB:YHR087W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HGI1
Summary
Involved in RNA metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RTC3 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (280820..281155)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Nam8p Neighboring gene uncharacterized protein Neighboring gene rRNA-binding ribosome biosynthesis protein RPF1 Neighboring gene H/ACA snoRNP pseudouridylase subunit GAR1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular response of Saccharomyces cerevisiae wine and laboratory strains to high sugar stress conditions. Jiménez-Martí E, et al. Int J Food Microbiol, 2011 Jan 31. PMID 21247650
  2. Genetic manipulation of HSP26 and YHR087W stress genes may improve fermentative behaviour in wine yeasts under vinification conditions. Jiménez-Martí E, et al. Int J Food Microbiol, 2009 Mar 31. PMID 19217680
  3. Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Boocock GR, et al. Genomics, 2006 Jun. PMID 16529906
  4. Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. Shammas C, et al. J Biol Chem, 2005 May 13. PMID 15701631
  5. Dissection of the elements of osmotic stress response transcription factor Hot1 involved in the interaction with MAPK Hog1 and in the activation of transcription. Gomar-Alba M, et al. Biochim Biophys Acta, 2013 Oct. PMID 23916462

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. YHR087W gene is highly expressed in the presence of high glucose concentrations. Deletion mutants present lower levels of several Hsp proteins.
    Title: Molecular response of Saccharomyces cerevisiae wine and laboratory strains to high sugar stress conditions.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in RNA metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rtc3p
NP_011955.1
  • hypothetical protein involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog is SDO1); null mutation suppresses cdc13-1 temperature sensitivity; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    280820..281155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179217.1 → NP_011955.1  TPA: Rtc3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011955.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DL39, P38804
    UniProtKB/TrEMBL
    A6ZSZ7, B3LSK5, C7GWV1, C8Z9N2, G2WFG2, N1P129
    Conserved Domains (1) summary
    pfam01172
    Location:6 → 95
    SBDS; Shwachman-Bodian-Diamond syndrome (SBDS) protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38804.1

Gene LinkOut

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