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aldose 1-epimerase superfamily protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 855808, updated on 2-Nov-2024

Summary

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Official Full Name
aldose 1-epimerase superfamily protein
Primary source
SGD:S000005354
Locus tag
YNR071C
See related
AllianceGenome:SGD:S000005354; FungiDB:YNR071C; VEuPathDB:YNR071C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Human ortholog(s) of this gene implicated in galactosemia 4. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (770440..771468, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Bsc5p Neighboring gene ATP-binding cassette multidrug transporter PDR18 Neighboring gene hexose transporter HXT17 Neighboring gene putative mannitol dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization. Li S, et al. J Biotechnol, 2013 Oct 10. PMID 23954547
  2. Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. Piya G, et al. PLoS One, 2015. PMID 25719602, Free PMC Article
  3. Chaperone control of the activity and specificity of the histone H3 acetyltransferase Rtt109. Fillingham J, et al. Mol Cell Biol, 2008 Jul. PMID 18458063, Free PMC Article
  4. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article
  5. The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. Atencio D, et al. G3 (Bethesda), 2014 Mar 20. PMID 24470217, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables aldose 1-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in galactose catabolic process via UDP-galactose IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
aldose 1-epimerase superfamily protein
NP_014469.1
  • Putative aldose 1-epimerase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    770440..771468 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183248.1 → NP_014469.1  TPA: aldose 1-epimerase superfamily protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014469.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1P6, P53757
    UniProtKB/TrEMBL
    A6ZSE5, B3LPH3, B5VR96, C7GM68, C8ZFU8
    Conserved Domains (1) summary
    cd09019
    Location:13 → 340
    galactose_mutarotase_like; galactose mutarotase_like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53757.1

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