U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

COG6 Golgi transport complex subunit COG6 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855687, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
COG6
Official Full Name
Golgi transport complex subunit COG6
Primary source
SGD:S000004986
Locus tag
YNL041C
See related
AllianceGenome:SGD:S000004986; FungiDB:YNL041C; VEuPathDB:YNL041C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
COD2; SEC37
Summary
Involved in cytoplasm to vacuole targeting by the Cvt pathway and intra-Golgi vesicle-mediated transport. Part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Orthologous to human COG6 (component of oligomeric golgi complex 6). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See COG6 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (549468..551987, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene uncharacterized protein Neighboring gene Bop3p Neighboring gene uncharacterized protein Neighboring gene putative alanine--tRNA ligase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mammalian ribosomal and chaperone protein RPS3A counteracts α-synuclein aggregation and toxicity in a yeast model system. De Graeve S, et al. Biochem J, 2013 Nov 1. PMID 23924367, Free PMC Article
  2. Cog1p plays a central role in the organization of the yeast conserved oligomeric Golgi complex. Fotso P, et al. J Biol Chem, 2005 Jul 29. PMID 15932880
  3. Molecular architecture of the complete COG tethering complex. Ha JY, et al. Nat Struct Mol Biol, 2016 Aug. PMID 27428773, Free PMC Article
  4. Detailed Analysis of the Interaction of Yeast COG Complex. Ishii M, et al. Cell Struct Funct, 2018 Jul 19. PMID 29899178, Free PMC Article
  5. The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic. Whyte JR, et al. Dev Cell, 2001 Oct. PMID 11703943

See all (86) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cytoplasm to vacuole targeting by the Cvt pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intra-Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in intra-Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Golgi transport complex IEA
Inferred from Electronic Annotation
more info
  
part_of Golgi transport complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Golgi transport complex subunit COG6
NP_014357.1
  • Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    549468..551987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182880.1 → NP_014357.1  TPA: Golgi transport complex subunit COG6 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014357.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZS37, D6W1D8, P53959
    UniProtKB/TrEMBL
    G2WM62, N1NY18
    Conserved Domains (1) summary
    smart01087
    Location:195 → 834
    COG6; Conserved oligomeric complex COG6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53959.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools