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FMP42 Fmp42p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855261, updated on 18-Sep-2024

Summary

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Official Symbol
FMP42
Official Full Name
Fmp42p
Primary source
SGD:S000004834
Locus tag
YMR221C
See related
AllianceGenome:SGD:S000004834; FungiDB:YMR221C; VEuPathDB:YMR221C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in fungal-type vacuole membrane and mitochondrion. Orthologous to human SLC43A1 (solute carrier family 43 member 1); SLC43A2 (solute carrier family 43 member 2); and SLC43A3 (solute carrier family 43 member 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See FMP42 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (713931..715445, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Esc1p Neighboring gene phosphomevalonate kinase Neighboring gene putative serine hydrolase Neighboring gene ubiquitin-specific protease UBP8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast vacuolar membrane proteome. Wiederhold E, et al. Mol Cell Proteomics, 2009 Feb. PMID 19001347
  2. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Fromont-Racine M, et al. Yeast, 2000 Jun 30. PMID 10900456, Free PMC Article
  3. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article
  4. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. McCormick MA, et al. Cell Metab, 2015 Nov 3. PMID 26456335, Free PMC Article
  5. Multiplex assay for condition-dependent changes in protein-protein interactions. Schlecht U, et al. Proc Natl Acad Sci U S A, 2012 Jun 5. PMID 22615397, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in fungal-type vacuole HDA PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fmp42p
NP_013948.1
  • hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy; targeted to vacuole via AP-3 pathway

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    713931..715445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182728.1 → NP_013948.1  TPA: Fmp42p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013948.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W046, Q04991
    UniProtKB/TrEMBL
    B3LMA9, C7GRD0, C8ZF85, G2WKS8, N1P5V0
    Conserved Domains (1) summary
    cl28910
    Location:11 → 205
    MFS; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04991.1

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