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SPG5 Spg5p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855229, updated on 2-Nov-2024

Summary

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Official Symbol
SPG5
Official Full Name
Spg5p
Primary source
SGD:S000004803
Locus tag
YMR191W
See related
AllianceGenome:SGD:S000004803; FungiDB:YMR191W; VEuPathDB:YMR191W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables proteasome binding activity. Involved in proteasome assembly. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SPG5 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (645656..646777)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene glycine decarboxylase subunit P Neighboring gene ATP-dependent DNA helicase SGS1 Neighboring gene Gyl1p Neighboring gene mitochondrial 54S ribosomal protein YmL24/YmL14

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spg5 protein regulates the proteasome in quiescence. Hanna J, et al. J Biol Chem, 2012 Oct 5. PMID 22904326, Free PMC Article
  2. Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Martinez MJ, et al. Mol Biol Cell, 2004 Dec. PMID 15456898, Free PMC Article
  3. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article
  4. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Collins SR, et al. Mol Cell Proteomics, 2007 Mar. PMID 17200106
  5. Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated. Voynova NS, et al. Eukaryot Cell, 2015 Dec. PMID 26432633, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables proteasome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables proteasome binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables proteasome binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteasome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
Spg5p
NP_013916.2
  • Protein required for proteasome assembly during quiescence; binds to base of the proteasome regulartory particle; required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    645656..646777
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182697.1 → NP_013916.2  TPA: Spg5p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013916.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W015, P42933
    UniProtKB/TrEMBL
    C8ZF55, N1P0H2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42933.3

Gene LinkOut

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