U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BMT5 25S rRNA (uracil2634-N3)-methyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 854711, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
BMT5
Official Full Name
25S rRNA (uracil2634-N3)-methyltransferase
Primary source
SGD:S000001358
Locus tag
YIL096C
See related
AllianceGenome:SGD:S000001358; FungiDB:YIL096C; VEuPathDB:YIL096C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables rRNA (uridine-N3-)-methyltransferase activity. Involved in rRNA base methylation. Located in nucleolus. Orthologous to human FDXACB1 (ferredoxin-fold anticodon binding domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See BMT5 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (182117..183127, complement)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Fmc1p Neighboring gene glucose-induced degradation complex subunit FYV10 Neighboring gene tRNA-Ile Neighboring gene serine/threonine protein kinase PRK1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae. Sharma S, et al. Nucleic Acids Res, 2014 Mar. PMID 24335083, Free PMC Article
  2. Probabilistic approach to predicting substrate specificity of methyltransferases. Szczepińska T, et al. PLoS Comput Biol, 2014 Mar. PMID 24651469, Free PMC Article
  3. Comprehensive structural and substrate specificity classification of the Saccharomyces cerevisiae methyltransferome. Wlodarski T, et al. PLoS One, 2011. PMID 21858014, Free PMC Article
  4. The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes. Wade CH, et al. Yeast, 2006 Mar. PMID 16544271
  5. The interplay between chromosome stability and cell cycle control explored through gene-gene interaction and computational simulation. Frumkin JP, et al. Nucleic Acids Res, 2016 Sep 30. PMID 27530428, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of BMT5 (YIL096C)as being responsible for m3U2634 methylation of the 25S rRNA.
    Title: Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (uridine-N3-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (uridine-N3-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (uridine-N3-)-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA base methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA base methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA base methylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus HDA PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
25S rRNA (uracil2634-N3)-methyltransferase
NP_012170.1
  • Methyltransferase required for m3U2634 methylation of the 25S rRNA; S-adenosylmethionine-dependent; associates with precursors of the 60S ribosomal subunit; predicted to be involved in ribosome biogenesis

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    182117..183127 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179444.1 → NP_012170.1  TPA: 25S rRNA (uracil2634-N3)-methyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012170.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVJ1, P40493
    UniProtKB/TrEMBL
    A6ZVI1, B3LTU3, C7GKM3, G2WG56, N1P0X5
    Conserved Domains (1) summary
    pfam10354
    Location:76 → 292
    DUF2431; Domain of unknown function (DUF2431)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40493.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools