TPO4 Tpo4p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: TPO4
Official Full Name: Tpo4p
Primary source: SGD:S000005799
Locus tag: YOR273C
See related: AllianceGenome:SGD:S000005799; FungiDB:YOR273C; VEuPathDB:YOR273C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables spermidine transmembrane transporter activity and spermine transmembrane transporter activity. Involved in spermidine transport and spermine transport. Located in fungal-type vacuole membrane and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables antiporter activity	IEA Inferred from Electronic Annotation more info
enables spermidine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables spermidine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables spermine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables spermine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in spermidine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in spermidine transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in spermidine transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spermine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in spermine transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in spermine transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
located_in fungal-type vacuole membrane	IMP Inferred from Mutant Phenotype more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

NP_014916.1

Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane

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The following sections contain reference sequences that belong to a specific genome build. Explain