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HER1 Her1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854402, updated on 18-Sep-2024

Summary

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Official Symbol
HER1
Official Full Name
Her1p
Primary source
SGD:S000005753
Locus tag
YOR227W
See related
AllianceGenome:SGD:S000005753; FungiDB:YOR227W; VEuPathDB:YOR227W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endoplasmic reticulum organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See HER1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (762825..766565)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase core subunit RPB8 Neighboring gene putative iron-binding protein ISU2 Neighboring gene Mcp1p Neighboring gene transcriptional modulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Federovitch CM, et al. Mol Biol Cell, 2008 Oct. PMID 18667535, Free PMC Article
  2. Bayesian Markov Random Field analysis for protein function prediction based on network data. Kourmpetis YA, et al. PLoS One, 2010 Feb 24. PMID 20195360, Free PMC Article
  3. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
  4. TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Muir A, et al. Elife, 2014 Oct 3. PMID 25279700, Free PMC Article
  5. Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Walsh EP, et al. Biochemistry, 2002 Feb 19. PMID 11841235

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
Her1p
NP_014870.1
  • hypothetical protein; required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments; HER1 has a paralog, GIP3, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    762825..766565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183646.1 → NP_014870.1  TPA: Her1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014870.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2T1, Q12276
    UniProtKB/TrEMBL
    C7GWF7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12276.1

Gene LinkOut

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