U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CMR2 Cmr2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854260, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CMR2
Official Full Name
Cmr2p
Primary source
SGD:S000005619
Locus tag
YOR093C
See related
AllianceGenome:SGD:S000005619; FungiDB:YOR093C; VEuPathDB:YOR093C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
DIP2
Summary
Located in cellular bud neck and cytosol. Orthologous to several human genes including DIP2B (disco interacting protein 2 homolog B) and DIP2C (disco interacting protein 2 homolog C). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CMR2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (497506..502452, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Tma46p Neighboring gene putative ATPase ECM3 Neighboring gene Arf family GTPase ARF3 Neighboring gene ribose-5-phosphate isomerase RKI1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. DIP2 is a unique regulator of diacylglycerol lipid homeostasis in eukaryotes. Mondal S, et al. Elife, 2022 Jun 29. PMID 35766356, Free PMC Article
  2. Bayesian Markov Random Field analysis for protein function prediction based on network data. Kourmpetis YA, et al. PLoS One, 2010 Feb 24. PMID 20195360, Free PMC Article
  3. Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Mok J, et al. Sci Signal, 2010 Feb 16. PMID 20159853, Free PMC Article
  4. Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. Chen Y, et al. Mol Cancer Res, 2005 Dec. PMID 16380504
  5. Snx4-assisted vacuolar targeting of transcription factors defines a new autophagy pathway for controlling ATG expression. Hanley SE, et al. Autophagy, 2021 Nov. PMID 33678121, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vacuole fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cellular bud neck HDA PubMed 
located_in cytosol HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in vacuole-mitochondrion membrane contact site IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Cmr2p
NP_014736.1
  • Protein involved in regulation of diacylglycerol lipids levels; deletion causes sensitivity to unfolded protein response-inducing agents

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    497506..502452 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183512.1 → NP_014736.1  TPA: Cmr2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014736.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2F4, Q12275
    UniProtKB/TrEMBL
    G2WMX0, N1NVS2
    Conserved Domains (3) summary
    cd05905
    Location:1004 → 1626
    Dip2; Disco-interacting protein 2 (Dip2)
    pfam06464
    Location:5 → 121
    DMAP_binding; DMAP1-binding Domain
    cl17068
    Location:179 → 893
    AFD_class_I; Adenylate forming domain, Class I superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12275.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools