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OPI10 Opi10p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854125, updated on 2-Nov-2024

Summary

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Official Symbol
OPI10
Official Full Name
Opi10p
Primary source
SGD:S000005392
Locus tag
YOL032W
See related
AllianceGenome:SGD:S000005392; FungiDB:YOL032W; VEuPathDB:YOL032W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable nuclear import signal receptor activity. Involved in inositol metabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 13. Orthologous to human HIKESHI (heat shock protein nuclear import factor hikeshi). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See OPI10 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (265429..266169)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene DNA repair ATPase SMC5 Neighboring gene glutamate--tRNA ligase MSE1 Neighboring gene Sil1p Neighboring gene 1,3-beta-glucanosyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables nuclear import signal receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in inositol metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Opi10p
NP_014610.1
  • Protein with a possible role in phospholipid biosynthesis; null mutant displays an inositol-excreting phenotype that is suppressed by exogenous choline; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    265429..266169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183286.1 → NP_014610.1  TPA: Opi10p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014610.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W233, Q08202
    UniProtKB/TrEMBL
    A6ZNH5, B3LJ25, B5VRL8, C7GK02, C8ZHT2, G2WMJ9, N1P2S8
    Conserved Domains (1) summary
    pfam05603
    Location:1 → 240
    DUF775; Protein of unknown function (DUF775)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08202.1

Gene LinkOut

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