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DDR2 Ddr2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854104, updated on 2-Nov-2024

Summary

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Official Symbol
DDR2
Official Full Name
Ddr2p
Primary source
SGD:S000005413
Locus tag
YOL052C-A
See related
AllianceGenome:SGD:S000005413; FungiDB:YOL052C-A; VEuPathDB:YOL052C-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YOL053C-A
Summary
Involved in several processes, including cellular response to heat; cellular response to hydrogen peroxide; and cellular response to starvation. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See DDR2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (231570..231755, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-protein ligase PSH1 Neighboring gene Aim39p Neighboring gene adenosylmethionine decarboxylase SPE2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evidence for a heat shock transcription factor-independent mechanism for heat shock induction of transcription in Saccharomyces cerevisiae. Kobayashi N, et al. Proc Natl Acad Sci U S A, 1990 Sep. PMID 2118651, Free PMC Article
  2. Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae. Kobayashi N, et al. Mol Cell Biol, 1993 Jan. PMID 8417330, Free PMC Article
  3. Structure and functional analysis of the multistress response gene DDR2 from Saccharomyces cerevisiae. Kobayashi N, et al. Biochem Biophys Res Commun, 1996 Dec 13. PMID 8954934
  4. Functional analysis of the stress response element and its role in the multistress response of Saccharomyces cerevisiae. Treger JM, et al. Biochem Biophys Res Commun, 1998 Feb 4. PMID 9473471
  5. DNA damage and heat shock dually regulate genes in Saccharomyces cerevisiae. McClanahan T, et al. Mol Cell Biol, 1986 Jan. PMID 3023840, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to heat IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to hydrogen peroxide IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in fungal-type vacuole HDA PubMed 

General protein information

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Preferred Names
Ddr2p
NP_014589.1
  • Multi-stress response protein; expression is activated by a variety of xenobiotic agents and environmental or physiological stresses; DDR2 has a paralog, HOR7, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    231570..231755 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183307.1 → NP_014589.1  TPA: Ddr2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014589.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W215, P89113
    UniProtKB/TrEMBL
    A6ZNF8, B3LJ07, C7GK19, C8ZHR1, G2WMI2, N1NWQ5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P89113.1

Gene LinkOut

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