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TDA10 putative ATP-dependent kinase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853119, updated on 2-Nov-2024

Summary

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Official Symbol
TDA10
Official Full Name
putative ATP-dependent kinase
Primary source
SGD:S000003437
Locus tag
YGR205W
See related
AllianceGenome:SGD:S000003437; FungiDB:YGR205W; VEuPathDB:YGR205W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables ATP binding activity. Predicted to be involved in phosphorylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See TDA10 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (909213..910085)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Neighboring gene uncharacterized protein Neighboring gene ubiquitin-binding ESCRT-I subunit protein MVB12 Neighboring gene Cir1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase. Li de La Sierra-Gallay I, et al. Proteins, 2004 Mar 1. PMID 14997573
  2. Sequencing of a 17.6 kb segment on the right arm of yeast chromosome VII reveals 12 ORFs, including CCT, ADE3 and TR-I genes, homologues of the yeast PMT and EF1G genes, of the human and bacterial electron-transferring flavoproteins (beta-chain) and of the Escherichia coli phosphoserine phosphohydrolase, and five new ORFs. Guerreiro P, et al. Yeast, 1996 Mar 15. PMID 8904340
  3. Pex19 is involved in importing dually targeted tail-anchored proteins to both mitochondria and peroxisomes. Cichocki BA, et al. Traffic, 2018 Oct. PMID 30033679
  4. Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Reid RJ, et al. Genome Res, 2011 Mar. PMID 21173034, Free PMC Article
  5. The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts. Scutenaire J, et al. Nucleic Acids Res, 2023 Jan 25. PMID 35934316, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative ATP-dependent kinase
NP_011721.3
  • ATP-binding hypothetical protein; crystal structure resembles that of E.coli pantothenate kinase and other small kinases; null mutant is sensitive to expression of the top1-T722A allele

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    909213..910085
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181334.3 → NP_011721.3  TPA: putative ATP-dependent kinase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011721.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUY8, P42938
    UniProtKB/TrEMBL
    A6ZUL6, B3LI31, B5VJE7, C7GRN8, C8Z998, G2WET4, N1P3Y7
    Conserved Domains (1) summary
    COG4240
    Location:1 → 287
    Tda10; Pantothenate kinase-related protein Tda10 (topoisomerase I damage affected protein) [General function prediction only]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42938.1

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