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MRX18 17-beta-hydroxysteroid dehydrogenase-like protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 852346, updated on 3-Nov-2024

Summary

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Official Symbol
MRX18
Official Full Name
17-beta-hydroxysteroid dehydrogenase-like protein
Primary source
SGD:S000000260
Locus tag
YBR056W
See related
AllianceGenome:SGD:S000000260; FungiDB:YBR056W; VEuPathDB:YBR056W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable glucan endo-1,6-beta-glucosidase activity. Predicted to be involved in glucan catabolic process. Located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MRX18 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (347879..349384)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene U4/U6-U5 snRNP complex subunit PRP6 Neighboring gene tRNA-Leu Neighboring gene tRNA-Gln Neighboring gene Mnc1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Chauhan N, et al. Yeast, 2020 Jan. PMID 31758572
  2. Intermembrane space proteome of yeast mitochondria. Vögtle FN, et al. Mol Cell Proteomics, 2012 Dec. PMID 22984289, Free PMC Article
  3. Pex19 is involved in importing dually targeted tail-anchored proteins to both mitochondria and peroxisomes. Cichocki BA, et al. Traffic, 2018 Oct. PMID 30033679
  4. Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis. Singh AP, et al. Mol Cell, 2020 Sep 17. PMID 32877643
  5. Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Hesselberth JR, et al. Genome Biol, 2006. PMID 16606443, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables beta-glucosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucan endo-1,6-beta-glucosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in glucan catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm HDA PubMed 
located_in cytosol HDA PubMed 
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
17-beta-hydroxysteroid dehydrogenase-like protein
NP_009612.1
  • Putative glycoside hydrolase of the mitochondrial intermembrane space

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    347879..349384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178404.1 → NP_009612.1  TPA: 17-beta-hydroxysteroid dehydrogenase-like protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009612.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQ55, P38081
    UniProtKB/TrEMBL
    A6ZKZ9, B3LN93, C7GSU2, D3UEF1, G2W961, N1P813
    Conserved Domains (1) summary
    COG2730
    Location:25 → 485
    BglC; Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38081.1

Gene LinkOut

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