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PLM2 Plm2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852112, updated on 18-Sep-2024

Summary

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Official Symbol
PLM2
Official Full Name
Plm2p
Primary source
SGD:S000002909
Locus tag
YDR501W
See related
AllianceGenome:SGD:S000002909; FungiDB:YDR501W; VEuPathDB:YDR501W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables chromatin binding activity. Involved in cellular response to DNA damage stimulus. Located in chromatin. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PLM2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1451353..1452918)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Lcd1p Neighboring gene ribosomal 60S subunit protein L37B Neighboring gene methionine adenosyltransferase SAM2 Neighboring gene phosphatidate phosphatase LPP1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae. Nautiyal S, et al. Proc Natl Acad Sci U S A, 2002 Jul 9. PMID 12084816, Free PMC Article
  2. Genotoxicity of chemical compounds identification and assessment by yeast cells transformed with GFP reporter constructs regulated by the PLM2 or DIN7 promoter. Bui VN, et al. Int J Toxicol, 2015 Jan-Feb. PMID 25691521
  3. The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway. Huang M, et al. Cold Spring Harb Symp Quant Biol, 2000. PMID 12760057
  4. Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Horak CE, et al. Genes Dev, 2002 Dec 1. PMID 12464632, Free PMC Article
  5. Genome-wide surveys for phosphorylation-dependent substrates of SCF ubiquitin ligases. Tang X, et al. Methods Enzymol, 2005. PMID 16338374

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genotoxicity of chemical compounds identification and assessment by yeast cells transformed with GFP reporter constructs regulated by the PLM2 or DIN7 promoter
    Title: Genotoxicity of chemical compounds identification and assessment by yeast cells transformed with GFP reporter constructs regulated by the PLM2 or DIN7 promoter.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Plm2p
NP_010789.1
  • Putative transcription factor, contains Forkhead Associated domain; found associated with chromatin; target of SBF transcription factor; induced in response to DNA damaging agents and deletion of telomerase; PLM2 has a paralog, TOS4, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1451353..1452918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180809.1 → NP_010789.1  TPA: Plm2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010789.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTC3, Q04383
    UniProtKB/TrEMBL
    A6ZZ90, B3LFG6, C8Z658, G2WBM9, N1P7P1
    Conserved Domains (1) summary
    cd00060
    Location:84 → 149
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04383.1

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