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NKP1 Nkp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851991, updated on 2-Nov-2024

Summary

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Official Symbol
NKP1
Official Full Name
Nkp1p
Primary source
SGD:S000002791
Locus tag
YDR383C
See related
AllianceGenome:SGD:S000002791; FungiDB:YDR383C; VEuPathDB:YDR383C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in cell division and meiotic cell cycle. Located in kinetochore. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See NKP1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1239960..1240676, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Coi1p Neighboring gene ribosomal protein P2B Neighboring gene putative ammonium permease ATO3 Neighboring gene elongation factor 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex. Deng S, et al. EMBO Rep, 2023 Dec 6. PMID 37983946, Free PMC Article
  2. Yeast Nkp2 is required for accurate chromosome segregation and interacts with several components of the central kinetochore. Tirupataiah S, et al. Mol Biol Rep, 2014 Feb. PMID 24385296
  3. The kinetochore prevents centromere-proximal crossover recombination during meiosis. Vincenten N, et al. Elife, 2015 Dec 14. PMID 26653857, Free PMC Article
  4. A TSC22-like motif defines a novel antiapoptotic protein family. Khoury CM, et al. FEMS Yeast Res, 2008 Jun. PMID 18355271, Free PMC Article
  5. The Structural Basis for Kinetochore Stabilization by Cnn1/CENP-T. Hinshaw SM, et al. Curr Biol, 2020 Sep 7. PMID 32679099

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nkp1p
NP_010671.4
  • Central kinetochore protein and subunit of the Ctf19 complex; mutants have elevated rates of chromosome loss; orthologous to fission yeast kinetochore protein fta4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1239960..1240676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180691.3 → NP_010671.4  TPA: Nkp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010671.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VT17, Q12493
    UniProtKB/TrEMBL
    A6ZYY4, B3LFR7, C7GMF1, G2WBC3, N1P5F7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12493.2

Gene LinkOut

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