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ESF1 pre-rRNA-processing protein ESF1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851969, updated on 18-Sep-2024

Summary

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Official Symbol
ESF1
Official Full Name
pre-rRNA-processing protein ESF1
Primary source
SGD:S000002773
Locus tag
YDR365C
See related
AllianceGenome:SGD:S000002773; FungiDB:YDR365C; VEuPathDB:YDR365C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables RNA binding activity. Involved in rRNA processing. Located in nucleolus. Orthologous to human ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ESF1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1204497..1206383, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene proteasome regulatory particle lid subunit SEM1 Neighboring gene Cdc40p Neighboring gene gag protein Neighboring gene gag-pol fusion protein Neighboring gene Mor1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae. Peng WT, et al. Nucleic Acids Res, 2004. PMID 15056729, Free PMC Article
  2. The helicase Has1p is required for snoRNA release from pre-rRNA. Liang XH, et al. Mol Cell Biol, 2006 Oct. PMID 16908538, Free PMC Article
  3. Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Hoang T, et al. Mol Cell Biol, 2005 Jul. PMID 15964808, Free PMC Article
  4. Nop9 is an RNA binding protein present in pre-40S ribosomes and required for 18S rRNA synthesis in yeast. Thomson E, et al. RNA, 2007 Dec. PMID 17956976, Free PMC Article
  5. Pwp2 mediates UTP-B assembly via two structurally independent domains. Boissier F, et al. Sci Rep, 2017 Jun 9. PMID 28600509, Free PMC Article

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleolus HDA PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
pre-rRNA-processing protein ESF1
NP_010653.1
  • Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1204497..1206383 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180673.1 → NP_010653.1  TPA: pre-rRNA-processing protein ESF1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010653.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSZ4, Q06344
    UniProtKB/TrEMBL
    A6ZYW4, B3LFT7, C7GMH1, C8Z5S7, G2WBA2, N1P717
    Conserved Domains (1) summary
    COG5638
    Location:1 → 608
    COG5638; Uncharacterized conserved protein [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06344.1

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