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MRX16 Mrx16p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851710, updated on 18-Sep-2024

Summary

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Official Symbol
MRX16
Official Full Name
Mrx16p
Primary source
SGD:S000002539
Locus tag
YDR132C
See related
AllianceGenome:SGD:S000002539; FungiDB:YDR132C; VEuPathDB:YDR132C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in protein homooligomerization. Located in mitochondrion and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MRX16 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (718816..720303, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Fin1p Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene ATP-binding cassette glutathione S-conjugate transporter YCF1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Menon BB, et al. Proc Natl Acad Sci U S A, 2005 Apr 19. PMID 15817685, Free PMC Article
  2. The ribosome receptors Mrx15 and Mba1 jointly organize cotranslational insertion and protein biogenesis in mitochondria. Möller-Hergt BV, et al. Mol Biol Cell, 2018 Oct 1. PMID 30091672, Free PMC Article
  3. Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes. del Alamo M, et al. PLoS Biol, 2011 Jul. PMID 21765803, Free PMC Article
  4. The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome. Niepel M, et al. Mol Biol Cell, 2013 Dec. PMID 24152732, Free PMC Article
  5. Annotating novel genes by integrating synthetic lethals and genomic information. Schöner D, et al. BMC Syst Biol, 2008 Jan 14. PMID 18194531, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein homooligomerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mrx16p
NP_010417.3
  • Protein that associates with the large mitoribosomal subunit; abundance and relative nuclear distribution to the protein increases upon DNA replication stress; YDR132C has a paralog, YLR108C, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    718816..720303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180440.3 → NP_010417.3  TPA: Mrx16p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010417.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSB8, Q03900
    UniProtKB/TrEMBL
    A6ZY93, B3LGE5, C7GIP0, C8Z548
    Conserved Domains (1) summary
    cd18316
    Location:30 → 121
    BTB_POZ_KCTD-like; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03900.1

Gene LinkOut

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