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PET100 Pet100p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851651, updated on 18-Sep-2024

Summary

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Official Symbol
PET100
Official Full Name
Pet100p
Primary source
SGD:S000002486
Locus tag
YDR079W
See related
AllianceGenome:SGD:S000002486; FungiDB:YDR079W; VEuPathDB:YDR079W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables unfolded protein binding activity. Involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrial inner membrane. Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PET100 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (603064..603399)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Sed1p Neighboring gene Shu2p Neighboring gene TFIIH complex subunit TFB5 Neighboring gene Vps41p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure and function of Pet100p, a molecular chaperone required for the assembly of cytochrome c oxidase in Saccharomyces cerevisiae. Forsha D, et al. Biochem Soc Trans, 2001 Aug. PMID 11498004
  2. Cloning and characterization of PET100, a gene required for the assembly of yeast cytochrome c oxidase. Church C, et al. J Biol Chem, 1996 Aug 2. PMID 8702496
  3. A role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant. Church C, et al. J Biol Chem, 2005 Jan 21. PMID 15507444
  4. Nutrient Control of Yeast Gametogenesis Is Mediated by TORC1, PKA and Energy Availability. Weidberg H, et al. PLoS Genet, 2016 Jun. PMID 27272508, Free PMC Article
  5. Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. Szklarczyk R, et al. Genome Biol, 2012 Feb 22. PMID 22356826, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pet100p functions in the holocytochrome c oxidase pathway to facilitate the interaction(s) between Complex A' and other cytochrome c oxidase subassemblies and subunits
    Title: A role for Pet100p in the assembly of yeast cytochrome c oxidase: interaction with a subassembly that accumulates in a pet100 mutant.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial cytochrome c oxidase assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial cytochrome c oxidase assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pet100p
NP_010364.1
  • Chaperone that facilitates the assembly of cytochrome c oxidase; integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    603064..603399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180387.1 → NP_010364.1  TPA: Pet100p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010364.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VS65, P38958
    UniProtKB/TrEMBL
    A6ZY44, B3LGJ1, C7GVQ8, C8Z4Z6, G2WAI3, N1P846
    Conserved Domains (1) summary
    pfam09803
    Location:15 → 78
    Pet100
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38958.1

Gene LinkOut

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