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MCH1 Mch1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851506, updated on 2-Nov-2024

Summary

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Official Symbol
MCH1
Official Full Name
Mch1p
Primary source
SGD:S000002212
Locus tag
YDL054C
See related
AllianceGenome:SGD:S000002212; FungiDB:YDL054C; VEuPathDB:YDL054C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MCH1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (359825..361285, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene mannose-1-phosphate guanylyltransferase Neighboring gene tRNA-Lys Neighboring gene Pbp4p Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase SLC1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane. Makuc J, et al. Yeast, 2001 Sep 15. PMID 11536335
  2. A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin. McLaughlin JE, et al. Proc Natl Acad Sci U S A, 2009 Dec 22. PMID 20007368, Free PMC Article
  3. Organelle acidification is important for localisation of vacuolar proteins in Saccharomyces cerevisiae. Matsumoto R, et al. Protoplasma, 2013 Dec. PMID 23708375
  4. A CRISPR/Cas9-based exploration into the elusive mechanism for lactate export in Saccharomyces cerevisiae. Mans R, et al. FEMS Yeast Res, 2017 Dec 1. PMID 29145596
  5. Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Menon BB, et al. Proc Natl Acad Sci U S A, 2005 Apr 19. PMID 15817685, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in fungal-type vacuole membrane HDA PubMed 
is_active_in fungal-type vacuole membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mch1p
NP_010229.1
  • Protein with similarity to mammalian monocarboxylate permeases; monocarboxylate permeases are involved in transport of monocarboxylic acids across the plasma membrane but mutant is not deficient in monocarboxylate transport

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    359825..361285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180113.1 → NP_010229.1  TPA: Mch1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010229.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRU2, Q07376
    UniProtKB/TrEMBL
    B3LGV2, B5VFL3, C8Z4L5, N1PAA3
    Conserved Domains (1) summary
    cd17314
    Location:27 → 465
    MFS_MCT_like; Monocarboxylate transporter (MCT) family and similar transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07376.1

Gene LinkOut

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