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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 850673, updated on 18-Sep-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000003976
Locus tag
YLL053C
See related
AllianceGenome:SGD:S000003976; FungiDB:YLL053C; VEuPathDB:YLL053C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable water channel activity. Predicted to be involved in transmembrane transport and water transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus. Orthologous to human AQP1 (aquaporin 1 (Colton blood group)) and AQP2 (aquaporin 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (35503..35961, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Yct1p Neighboring gene uncharacterized protein Neighboring gene Aqy2p Neighboring gene putative ferric-chelate reductase Neighboring gene cofilin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polymorphism of Saccharomyces cerevisiae aquaporins. Laizé V, et al. Yeast, 2000 Jul. PMID 10870101
  2. Existence of a tightly regulated water channel in Saccharomyces cerevisiae. Meyrial V, et al. Eur J Biochem, 2001 Jan. PMID 11168368
  3. Aquaporins in Saccharomyces: Characterization of a second functional water channel protein. Carbrey JM, et al. Proc Natl Acad Sci U S A, 2001 Jan 30. PMID 11158584, Free PMC Article
  4. Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains. Tanghe A, et al. Appl Environ Microbiol, 2002 Dec. PMID 12450819, Free PMC Article
  5. Functional analysis of eight open reading frames on chromosomes XII and XIV of Saccharomyces cerevisiae. Ahmed Khan S, et al. Yeast, 2000 Dec. PMID 11113969

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables channel activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables water channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in water transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_013047.1
  • Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    35503..35961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181873.1 → NP_013047.1  TPA: uncharacterized protein YLL053C [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013047.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A7A0K7, B3LTC4, C7GNE2, C8ZCS2, D6VXV5, P0CD98
    Conserved Domains (1) summary
    cl00200
    Location:1 → 133
    MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CD98.1

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