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UREG_06116 GTP-binding protein LepA [ Uncinocarpus reesii 1704 ]

Gene ID: 8443270, updated on 31-Oct-2024

Summary

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Gene symbol
UREG_06116
Gene description
GTP-binding protein LepA
Locus tag
UREG_06116
See related
FungiDB:UREG_06116; VEuPathDB:UREG_06116
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Uncinocarpus reesii 1704 (strain: 1704)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus
Orthologs
Aspergillus fumigatus all
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Genomic context

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See UREG_06116 in Genome Data Viewer
Location:
chromosome: Unknown
Exon count:
2

NW_003052497.1Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase III largest subunit Neighboring gene mitotic spindle checkpoint component mad2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003052497.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives. Sharpton TJ, et al. Genome Res, 2009 Oct. PMID 19717792, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mitochondrial ribosome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTP-binding protein LepA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NW_003052497.1 Reference assembly

    Range
    48296..50345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002583103.1 → XP_002583149.1  GTP-binding protein LepA [Uncinocarpus reesii 1704]

    See identical proteins and their annotated locations for XP_002583149.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    C4JWU3
    Conserved Domains (6) summary
    cd01890
    Location:68 → 244
    LepA; LepA also known as Elongation Factor 4 (EF4)
    COG0481
    Location:62 → 662
    LepA; Translation elongation factor EF-4, membrane-bound GTPase [Translation, ribosomal structure and biogenesis]
    cd03709
    Location:469 → 548
    lepA_C; lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits ...
    pfam06421
    Location:556 → 662
    LepA_C; GTP-binding protein LepA C-terminus
    cd03699
    Location:252 → 338
    EF4_II; Domain II of Elongation Factor 4 (EF4)
    cd16260
    Location:358 → 432
    EF4_III; Domain III of Elongation Factor 4 (EF4)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C4JWU3.1

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