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Terpenoid cyclases family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 844186, updated on 18-Sep-2024

Summary

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Official Full Name
Terpenoid cyclases family protein
Primary source
TAIR:AT1G78500
Locus tag
AT1G78500
See related
Araport:AT1G78500
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
PEN6; PENTACYCLIC TRITERPENE SYNTHASE 6; T30F21.16; T30F21_16
Summary
Encodes a protein with pentacyclic triterpene synthase activity. In addition to the compounds lupeol, alpha-amyrin and bauerenol, this enzyme was also shown to produce two <i>seco</i>-triterpenes: alpha- and beta-<i>seco</i>-amyrin.
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Sequence:
Chromosome: 1; NC_003070.9 (29531467..29535204)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Prenyltransferase family protein Neighboring gene cytochrome P450, family 708, subfamily A, polypeptide 3 Neighboring gene solanesyl diphosphate synthase 1 Neighboring gene Carbohydrate-binding X8 domain superfamily protein Neighboring gene Protein kinase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Origin of structural diversity in natural triterpenes: direct synthesis of seco-triterpene skeletons by oxidosqualene cyclase. Shibuya M, et al. J Am Chem Soc, 2007 Feb 7. PMID 17263431
  2. Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. Husselstein-Muller T, et al. Plant Mol Biol, 2001 Jan. PMID 11247608
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lupeol synthase activity TAS
Traceable Author Statement
more info
 PubMed 
enables oxidosqualene cyclase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in triterpenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Terpenoid cyclases family protein
NP_177971.1
  • Terpenoid cyclases family protein; CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: baruol synthase 1 (TAIR:AT4G15370.1); Has 1985 Blast hits to 1925 proteins in 565 species: Archae - 4; Bacteria - 842; Metazoa - 93; Fungi - 239; Plants - 602; Viruses - 0; Other Eukaryotes - 205 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    29531467..29535204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001334828.1 → NP_001322480.1  Terpenoid cyclases family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SYN1
    UniProtKB/TrEMBL
    A0A5S9WVG9, A0A654EQB4
    Conserved Domains (1) summary
    PLN03012
    Location:1 → 766
    PLN03012; Camelliol C synthase

  2. NM_106497.1 → NP_177971.1  Terpenoid cyclases family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177971.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SYN1
    UniProtKB/TrEMBL
    A0A5S9WVG9, A0A654EQB4
    Conserved Domains (1) summary
    PLN03012
    Location:1 → 766
    PLN03012; Camelliol C synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SYN1.1

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