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CP12-3 CP12 domain-containing protein 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843989, updated on 18-Sep-2024

Summary

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Official Symbol
CP12-3
Official Full Name
CP12 domain-containing protein 3
Primary source
TAIR:AT1G76560
Locus tag
AT1G76560
See related
Araport:AT1G76560
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CP12 domain-containing protein 3; F14G6.16; F14G6_16
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Genomic context

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See CP12-3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_003070.9 (28728206..28728976)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Auxin efflux carrier family protein Neighboring gene cyclin-dependent kinase B2;1 Neighboring gene Phosphofructokinase family protein Neighboring gene Chlorophyll A-B binding family protein Neighboring gene Squamosa promoter-binding protein-like (SBP domain) transcription factor family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis CP12 mutants have reduced levels of phosphoribulokinase and impaired function of the Calvin-Benson cycle. Elena López-Calcagno P, et al. J Exp Bot, 2017 Apr 1. PMID 28430985, Free PMC Article
  2. CP12-mediated protection of Calvin-Benson cycle enzymes from oxidative stress. Marri L, et al. Biochimie, 2014 Feb. PMID 24211189
  3. In vitro characterization of Arabidopsis CP12 isoforms reveals common biochemical and molecular properties. Marri L, et al. J Plant Physiol, 2010 Aug 15. PMID 20399532
  4. Expression analysis of the Arabidopsis CP12 gene family suggests novel roles for these proteins in roots and floral tissues. Singh P, et al. J Exp Bot, 2008. PMID 18974062, Free PMC Article
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Single cp12-1, cp12-2, and cp12-3 mutants do not develop a severe photosynthetic or growth phenotype. In contrast, reductions of both CP12-1 and CP12-2 transcripts lead to reductions in photosynthetic capacity and to slower growth and reduced seed yield. No clear phenotype for CP12-3 was evident.
    Title: Arabidopsis CP12 mutants have reduced levels of phosphoribulokinase and impaired function of the Calvin-Benson cycle.
  2. CP12 in oxygen phototrophs needs to be extended beyond light/dark regulation, and include protection of enzymes belonging to Calvine-Benson cycle from oxidative stress.
    Title: CP12-mediated protection of Calvin-Benson cycle enzymes from oxidative stress.
  3. All CP12 isoforms formed, in vitro, a supramolecular complex with GAPDH and PRK, with comparable inhibitory effects on both enzyme activities.
    Title: In vitro characterization of Arabidopsis CP12 isoforms reveals common biochemical and molecular properties.
  4. CP12-1 and CP12-2 expression was detected in the sepals and the style of the flower, while CP12-3 was restricted to the stigma and anthers.
    Title: Expression analysis of the Arabidopsis CP12 gene family suggests novel roles for these proteins in roots and floral tissues.
Submit: New GeneRIF Correction

General gene information

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NM_106306.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables nickel cation binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in cellular response to anoxia IEP
Inferred from Expression Pattern
more info
 PubMed 
NOT involved_in cellular response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to heat IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within negative regulation of reductive pentose-phosphate cycle IDA
Inferred from Direct Assay
more info
 PubMed 
NOT involved_in response to light stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
CP12 domain-containing protein 3
NP_565134.1
  • CP12 domain-containing protein 3 (CP12-3); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: negative regulation of reductive pentose-phosphate cycle; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function CP12 (InterPro:IPR003823); BEST Arabidopsis thaliana protein match is: CP12 domain-containing protein 1 (TAIR:AT2G47400.1); Has 242 Blast hits to 242 proteins in 66 species: Archae - 0; Bacteria - 121; Metazoa - 0; Fungi - 0; Plants - 114; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    28728206..28728976
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_106306.3 → NP_565134.1  CP12 domain-containing protein 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565134.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LEL6, Q9C9K2
    UniProtKB/TrEMBL
    A0A178WDK7, A0A5S9WUY3
    Conserved Domains (1) summary
    pfam02672
    Location:65 → 133
    CP12; CP12 domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C9K2.1

Gene LinkOut

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