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Pyridine nucleotide-disulfide oxidoreductase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843788, updated on 18-Sep-2024

Summary

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Official Full Name
Pyridine nucleotide-disulfide oxidoreductase family protein
Primary source
TAIR:AT1G74470
Locus tag
AT1G74470
See related
Araport:AT1G74470
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F1M20.15; F1M20_15; GERANYLGERANYL REDUCTASE
Summary
Encodes for a multifunctional protein with geranylgeranyl reductase activity shown to catalyze the reduction of prenylated geranylgeranyl-chlorophyll a to phytyl-chlorophyll a (chlorophyll a) and free geranylgeranyl pyrophosphate to phytyl pyrophosphate.
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Genomic context

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Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (27991165..27993445)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene RWP-RK domain-containing protein Neighboring gene Protein kinase superfamily protein Neighboring gene activation-tagged BRI1(brassinosteroid-insensitive 1)-suppressor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Metabolic compartmentation of plastid prenyllipid biosynthesis--evidence for the involvement of a multifunctional geranylgeranyl reductase. Keller Y, et al. Eur J Biochem, 1998 Jan 15. PMID 9492312
  2. Arabidopsis GERANYLGERANYL DIPHOSPHATE SYNTHASE 11 is a hub isozyme required for the production of most photosynthesis-related isoprenoids. Ruiz-Sola MÁ, et al. New Phytol, 2016 Jan. PMID 26224411
  3. LIL3, a light-harvesting-like protein, plays an essential role in chlorophyll and tocopherol biosynthesis. Tanaka R, et al. Proc Natl Acad Sci U S A, 2010 Sep 21. PMID 20823244, Free PMC Article
  4. Identification of proteins that interact with catalytically active calcium-dependent protein kinases from Arabidopsis. Uno Y, et al. Mol Genet Genomics, 2009 Apr. PMID 19130088
  5. New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy. Peltier JB, et al. J Biol Chem, 2004 Nov 19. PMID 15322131

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_106107.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables geranylgeranyl diphosphate reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables geranylgeranyl reductase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables geranylgeranyl reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within chlorophyll biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chlorophyll biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in vitamin E biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast envelope HDA PubMed 
located_in chloroplast thylakoid HDA PubMed 
located_in chloroplast thylakoid membrane HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
Pyridine nucleotide-disulfide oxidoreductase family protein
NP_177587.1
  • Pyridine nucleotide-disulphide oxidoreductase family protein; FUNCTIONS IN: geranylgeranyl reductase activity; INVOLVED IN: chlorophyll biosynthetic process; LOCATED IN: chloroplast thylakoid membrane, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Geranylgeranyl reductase (InterPro:IPR010253), Geranylgeranyl reductase, plant/cyanobacteria (InterPro:IPR011774), Geranylgeranyl reductase, plant/prokaryotic (InterPro:IPR011777); Has 4540 Blast hits to 4539 proteins in 1185 species: Archae - 562; Bacteria - 2644; Metazoa - 5; Fungi - 25; Plants - 302; Viruses - 0; Other Eukaryotes - 1002 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    27991165..27993445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_106107.3 → NP_177587.1  Pyridine nucleotide-disulfide oxidoreductase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177587.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DHM2, O49594, Q56YY5, Q8H170, Q9CA67
    UniProtKB/TrEMBL
    A0A178W817, A0A5S9WUC6
    Conserved Domains (1) summary
    PLN00093
    Location:17 → 467
    PLN00093; geranylgeranyl diphosphate reductase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CA67.1

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