Leucine-rich receptor-like protein kinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Full Name: Leucine-rich receptor-like protein kinase family protein
Primary source: TAIR:AT1G72180
Locus tag: AT1G72180
See related: Araport:AT1G72180
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: C-terminally encoded peptide receptor 2; CEPR2; T9N14.3; T9N14_3
Summary: Encodes a leucine-rich repeat receptor kinase that functions as a receptor for CEP1 peptide. Mediates nitrate uptake signaling.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 4

Sequence:: Chromosome: 1; NC_003070.9 (27162820..27167430)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Regulation of the stability and ABA import activity of NRT1.2/NPF4.6 by CEPR2-mediated phosphorylation in Arabidopsis.
Title: Regulation of the stability and ABA import activity of NRT1.2/NPF4.6 by CEPR2-mediated phosphorylation in Arabidopsis.
Loss of function by T-DNA insertion in C-terminally encoded peptide receptor 2 (CEPR2) together with phloem intercalated with xylem (PXY) and PXY-Like 2 (PXL2) led to abscisic acid (ABA) hypersensitivity, while CEPR2 overexpression led to ABA insensitivity compared with the wild type, indicating the redundant and negative roles of CEPR2, PXY, and PXL2 in ABA signaling.
Title: CEPR2 phosphorylates and accelerates the degradation of PYR/PYLs in Arabidopsis.
this study concluded that two LRR-RKs At5g49660 and At1g72180 function as CEP receptors and named them CEPR1 and CEPR2.
Title: Perception of root-derived peptides by shoot LRR-RKs mediates systemic N-demand signaling.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_105877.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables peptide binding	IDA Inferred from Direct Assay more info	PubMed
enables peptide binding	IPI Inferred from Physical Interaction more info	PubMed
enables peptide hormone binding	IDA Inferred from Direct Assay more info	PubMed
enables peptide receptor activity	IGI Inferred from Genetic Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transmembrane receptor protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within nitrate import	IGI Inferred from Genetic Interaction more info	PubMed
involved_in nitrate import	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of root development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of shoot system development	IGI Inferred from Genetic Interaction more info	PubMed
involved_in response to mannitol	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to nitrate starvation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in response to osmotic stress	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	ISM Inferred from Sequence Model more info

General protein information

Go to the top of the page Help

Preferred Names: Leucine-rich receptor-like protein kinase family protein

NP_177363.1

Leucine-rich receptor-like protein kinase family protein; FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity, ATP binding; INVOLVED IN: transmembrane receptor protein tyrosine kinase signaling pathway, protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: HAESA-like 1 (TAIR:AT1G28440.1); Has 222922 Blast hits to 143384 proteins in 4612 species: Archae - 143; Bacteria - 22250; Metazoa - 69718; Fungi - 11673; Plants - 90830; Viruses - 408; Other Eukaryotes - 27900 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

27162820..27167430

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_105877.3 → NP_177363.1 Leucine-rich receptor-like protein kinase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_177363.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0WPH6, Q9C7T7

UniProtKB/TrEMBL

A0A178WLL8

Conserved Domains (2) summary

sd00033
Location:100 → 123

LRR_RI; leucine-rich repeat [structural motif]

cl26793
Location:19 → 961

PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional