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UKL3 uridine kinase-like 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842031, updated on 18-Sep-2024

Summary

Official Symbol
UKL3
Official Full Name
uridine kinase-like 3
Primary source
TAIR:AT1G55810
Locus tag
AT1G55810
See related
Araport:AT1G55810
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F20N2.21; F20N2_21; uridine kinase-like 3
Summary
One of the homologous genes predicted to encode proteins with UPRT domains (Uracil phosphoribosyltransferase). Five of these genes (At5g40870, At3g27190, At1g55810, At4g26510 and At3g27440) show a high level of identity, and are annotated as also containing a N-terminal uracil kinase (UK) domain. These genes are referred to as UKL1 (UK-like 1), UKL2, UKL3, UKL4 and UKL5, respectively.
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Genomic context

See UKL3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Sequence:
Chromosome: 1; NC_003070.9 (20860507..20864287)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ferredoxin-fold anticodon-binding domain protein Neighboring gene BolA-like family protein Neighboring gene lysine-specific demethylase, putative (DUF1296) Neighboring gene coiled-coil protein Neighboring gene Sec14p-like phosphatidylinositol transfer family protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_001333734.1
NM_001333735.1
NM_001333736.1
NM_001333737.1
NM_104458.4
NM_202307.3
NM_202308.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables uracil phosphoribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables uridine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in CTP salvage IEA
Inferred from Electronic Annotation
more info
 
involved_in UMP salvage IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 

General protein information

Preferred Names
uridine kinase-like 3
NP_175977.1
  • uridine kinase-like 3 (UKL3); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 12937 Blast hits to 12923 proteins in 2615 species: Archae - 215; Bacteria - 9909; Metazoa - 552; Fungi - 508; Plants - 588; Viruses - 2; Other Eukaryotes - 1163 (source: NCBI BLink).
NP_974036.2
  • uridine kinase-like 3 (UKL3); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 12796 Blast hits to 12782 proteins in 2591 species: Archae - 213; Bacteria - 9841; Metazoa - 556; Fungi - 487; Plants - 538; Viruses - 2; Other Eukaryotes - 1159 (source: NCBI BLink).
NP_974037.1
  • uridine kinase-like 3 (UKL3); FUNCTIONS IN: uracil phosphoribosyltransferase activity, phosphotransferase activity, alcohol group as acceptor, kinase activity, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20860507..20864287
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_202307.3NP_974036.2  uridine kinase-like 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974036.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WDH0
    Conserved Domains (3) summary
    COG0572
    Location:43249
    Udk; Uridine kinase [Nucleotide transport and metabolism]
    cd02023
    Location:46244
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
    pfam14681
    Location:262458
    UPRTase; Uracil phosphoribosyltransferase
  2. NM_202308.2NP_974037.1  uridine kinase-like 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974037.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MQ84, Q8VYB2, Q9LG32
    UniProtKB/TrEMBL
    A0A178WDH0
    Conserved Domains (3) summary
    COG0572
    Location:43249
    Udk; Uridine kinase [Nucleotide transport and metabolism]
    cd02023
    Location:46244
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
    pfam14681
    Location:262463
    UPRTase; Uracil phosphoribosyltransferase
  3. NM_104458.4NP_175977.1  uridine kinase-like 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175977.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MQ84, Q8VYB2, Q9LG32
    UniProtKB/TrEMBL
    A0A178WDH0
    Conserved Domains (3) summary
    COG0572
    Location:43249
    Udk; Uridine kinase [Nucleotide transport and metabolism]
    cd02023
    Location:46244
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
    pfam14681
    Location:262463
    UPRTase; Uracil phosphoribosyltransferase
  4. NM_001333734.1NP_001323276.1  uridine kinase-like 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WDH0, A0A1P8AWM1
  5. NM_001333735.1NP_001323275.1  uridine kinase-like 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WDH0, A0A1P8AWM1
  6. NM_001333736.1NP_001323277.1  uridine kinase-like 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MQ84, Q8VYB2, Q9LG32
    UniProtKB/TrEMBL
    A0A178WDH0
  7. NM_001333737.1NP_001323278.1  uridine kinase-like 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WDD0, A0A1P8AWK0