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GAPB glyceraldehyde-3-phosphate dehydrogenase B subunit [ Arabidopsis thaliana (thale cress) ]

Gene ID: 840895, updated on 18-Sep-2024

Summary

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Official Symbol
GAPB
Official Full Name
glyceraldehyde-3-phosphate dehydrogenase B subunit
Primary source
TAIR:AT1G42970
Locus tag
AT1G42970
See related
Araport:AT1G42970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F13A11.3; F13A11_3; glyceraldehyde-3-phosphate dehydrogenase B subunit; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE B SUBUNIT
Summary
Encodes chloroplast localized glyceraldehyde-3-phosphate dehydrogenase that can use both NADH and NADPH to reduce 1,3-diphosphate glycerate. It forms A2B2 heterotetramers with GapA forms of the GADPH enzyme. These complexes are active in the light under reducing conditions, but show reduced NADPH-dependent activity in response to oxidized thioredoxins and increased NAD(H)/NADP(H) ratios due to the formation of inactive A8B8 hexadecamers.
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Genomic context

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See GAPB in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (16127353..16129895)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene inner membrane localized protein Neighboring gene ncRNA Neighboring gene Actin-binding FH2 (formin homology 2) family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and chromosomal mapping of nuclear genes encoding chloroplast and cytosolic glyceraldehyde-3-phosphate-dehydrogenase from Arabidopsis thaliana. Shih MC, et al. Gene, 1992 Oct 1. PMID 1398114
  2. Reconstitution and properties of the recombinant glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase supramolecular complex of Arabidopsis. Marri L, et al. Plant Physiol, 2005 Nov. PMID 16258009, Free PMC Article
  3. Co-ordinated gene expression of photosynthetic glyceraldehyde-3-phosphate dehydrogenase, phosphoribulokinase, and CP12 in Arabidopsis thaliana. Marri L, et al. J Exp Bot, 2005 Jan. PMID 15533878
  4. Identification of multiple salicylic acid-binding proteins using two high throughput screens. Manohar M, et al. Front Plant Sci, 2014. PMID 25628632, Free PMC Article
  5. The chloroplast lumen and stromal proteomes of Arabidopsis thaliana show differential sensitivity to short- and long-term exposure to low temperature. Goulas E, et al. Plant J, 2006 Sep. PMID 16923014

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_103456.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity IEA
Inferred from Electronic Annotation
more info
  
enables glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables salicylic acid binding HDA PubMed 
Process Evidence Code Pubs
involved_in glucose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in reductive pentose-phosphate cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within reductive pentose-phosphate cycle NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to light stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to sucrose IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in chloroplast envelope HDA PubMed 
located_in chloroplast stroma HDA PubMed 
located_in chloroplast thylakoid membrane HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in stromule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glyceraldehyde-3-phosphate dehydrogenase B subunit
NP_174996.1
  • glyceraldehyde-3-phosphate dehydrogenase B subunit (GAPB); FUNCTIONS IN: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity, glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: in 6 processes; LOCATED IN: in 7 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828), Protein of unknown function CP12 (InterPro:IPR003823); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 24904 Blast hits to 24897 proteins in 6198 species: Archae - 41; Bacteria - 10859; Metazoa - 2228; Fungi - 2814; Plants - 3753; Viruses - 0; Other Eukaryotes - 5209 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    16127353..16129895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_103456.4 → NP_174996.1  glyceraldehyde-3-phosphate dehydrogenase B subunit [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_174996.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P25857, Q0WL92, Q9C7S2
    UniProtKB/TrEMBL
    A0A5S9WM95, A0A654EFT5, A0A7G2DYG1
    Conserved Domains (1) summary
    PLN02237
    Location:3 → 447
    PLN02237; glyceraldehyde-3-phosphate dehydrogenase B
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25857.2

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