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Slmap sarcolemma associated protein [ Mus musculus (house mouse) ]

Gene ID: 83997, updated on 2-Nov-2024

Summary

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Official Symbol
Slmapprovided by MGI
Official Full Name
sarcolemma associated proteinprovided by MGI
Primary source
MGI:MGI:1933549
See related
Ensembl:ENSMUSG00000021870 AllianceGenome:MGI:1933549
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Slap; Miranda; mKIAA1601; D330001L02Rik
Summary
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; regulation of membrane depolarization during cardiac muscle cell action potential; and regulation of voltage-gated sodium channel activity. Located in membrane. Is expressed in heart. Orthologous to human SLMAP (sarcolemma associated protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in bladder adult (RPKM 44.9), adrenal adult (RPKM 22.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Slmap in Genome Data Viewer
Location:
14 A3; 14 16.09 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (26134323..26256103, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (26413168..26534624, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933413J09 gene Neighboring gene STARR-seq mESC enhancer starr_36233 Neighboring gene predicted gene, 52114 Neighboring gene predicted gene, 34223 Neighboring gene STARR-seq mESC enhancer starr_36237 Neighboring gene predicted gene, 24031 Neighboring gene STARR-seq mESC enhancer starr_36239 Neighboring gene ribosomal protein L34 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1167 Neighboring gene STARR-seq mESC enhancer starr_36240 Neighboring gene Kruppel-like factor 17 pseudogene Neighboring gene ribosomal protein S8 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation. Dias AP, et al. Open Biol, 2024 Oct. PMID 39417621, Free PMC Article
  2. A novel isoform of sarcolemmal membrane-associated protein (SLMAP) is a component of the microtubule organizing centre. Guzzo RM, et al. J Cell Sci, 2004 May 1. PMID 15126628
  3. Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice. Chen X, et al. Exp Diabetes Res, 2011. PMID 21785580, Free PMC Article
  4. SLMAP3 isoform modulates cardiac gene expression and function. Mlynarova J, et al. PLoS One, 2019. PMID 30934005, Free PMC Article
  5. Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum. Nader M, et al. Am J Physiol Heart Circ Physiol, 2012 Mar 1. PMID 22180652

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation.
    Title: SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation.
  2. SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.
    Title: SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.
  3. Manipulation of the nuclear envelope-associated protein SLAP during mammalian brain development affects cortical lamination and exploratory behavior.
    Title: Manipulation of the nuclear envelope-associated protein SLAP during mammalian brain development affects cortical lamination and exploratory behavior.
  4. A novel role for SLMAP3 in the selective regulation of important ion transport proteins at the level of gene expression and this suggests that it may be a unique target in cardiovascular function and diseases.
    Title: SLMAP3 isoform modulates cardiac gene expression and function.
  5. These data demonstrate that SLMAP is a regulator of E-C coupling at the level of the SR and its perturbation results in progressive deterioration of cardiac electrophysiology and function.
    Title: Tail-anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum.
  6. SLMAP may be an important regulator of glucose uptake or involved in GLUT-4 fusion/translocation into the plasma membrane of mouse abdominal adipose tissue; changes in SLMAP expression are linked to hyperglycemia and diabetes.
    Title: Increased expression of the tail-anchored membrane protein SLMAP in adipose tissue from type 2 Tally Ho diabetic mice.
  7. the genomic structure; SLMAP sequences directed a reporter green fluorescent protein (GFP) to the centrosome, and deletions of the newly identified N-terminal sequence from SLMAP prevented the centrosomal targeting
    Title: A novel isoform of sarcolemmal membrane-associated protein (SLMAP) is a component of the microtubule organizing centre.
  8. Microvasculature in db/db mice undergoes significant changes in vascular function with endothelial component of vascular dysfunction specifically correlating with overexpression of SLMAP.
    Title: Endothelial dysfunction in Type 2 diabetes correlates with deregulated expression of the tail-anchored membrane protein SLMAP.
  9. The cardiac-specific expression of SLMAP isoforms that can be targeted to distinct subcellular membranes, self assemble, and interact with the myofibril suggests a potential role in the structural arrangement of the E-C coupling apparatus.
    Title: Molecular properties of cardiac tail-anchored membrane protein SLMAP are consistent with structural role in arrangement of excitation-contraction coupling apparatus.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Targeted (1) 
  • Transposon induced (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA1601

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-macromolecule adaptor activity ISO
Inferred from Sequence Orthology
more info
  
enables protein-macromolecule adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of hippo signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of hippo signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of hippo signaling ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of membrane depolarization during cardiac muscle cell action potential IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of membrane depolarization during cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of sodium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of voltage-gated sodium channel activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of FAR/SIN/STRIPAK complex ISO
Inferred from Sequence Orthology
more info
  
part_of FAR/SIN/STRIPAK complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in M band IEA
Inferred from Electronic Annotation
more info
  
located_in Z disc IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sarcolemmal membrane-associated protein
Names
sarcolemmal-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310445.1 → NP_001297374.1  sarcolemmal membrane-associated protein isoform 1

    See identical proteins and their annotated locations for NP_001297374.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AK141597, AK164911, BP762661, DV646594, DV651439, DV655219
    Consensus CDS
    CCDS79284.1
    UniProtKB/Swiss-Prot
    Q3TLP0, Q3UIZ6, Q3URD3, Q6ZPL8, Q8VC86, Q9EQ03
    UniProtKB/TrEMBL
    F8WIH0
    Related
    ENSMUSP00000117816.2, ENSMUST00000139075.8
    Conserved Domains (5) summary
    COG1716
    Location:46 → 109
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 812
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam07851
    Location:680 → 775
    TMPIT; TMPIT-like protein
    cl19219
    Location:297 → 367
    DUF342; Protein of unknown function (DUF342)

  2. NM_001347494.1 → NP_001334423.1  sarcolemmal membrane-associated protein isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks three consecutive alternate in-frame exons in the central coding region compared to variant 1. It encodes isoform 3 which has the same N- and C-termini, but is shorter, and has a single internal aa difference compared to isoform 1.
    Source sequence(s)
    AK141597, AK164911, BP762661, CA539668, CK619354, CO432990, DV646594, DV651439, DV655219
    Consensus CDS
    CCDS84099.1
    UniProtKB/TrEMBL
    D3Z7V3, F8WIH0
    Related
    ENSMUSP00000107949.2, ENSMUST00000112330.8
    Conserved Domains (3) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 757
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  3. NM_032008.4 → NP_114397.3  sarcolemmal membrane-associated protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region and contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2 which differs in the central region of the protein and has a distinct and shorter C-terminus compared to isoform 1.
    Source sequence(s)
    AK164911, BP762661, CK619354, CO432990, CX205605, DV646594, DV651439, DV655219
    Consensus CDS
    CCDS26880.1
    UniProtKB/TrEMBL
    F8WIH0
    Related
    ENSMUSP00000046956.4, ENSMUST00000038522.10
    Conserved Domains (5) summary
    COG1716
    Location:46 → 109
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 791
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam07851
    Location:659 → 754
    TMPIT; TMPIT-like protein
    cl19219
    Location:297 → 367
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    26134323..26256103 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158935.1 → XP_036014828.1  sarcolemmal membrane-associated protein isoform X28

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG0419
    Location:167 → 717
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  2. XM_036158925.1 → XP_036014818.1  sarcolemmal membrane-associated protein isoform X14

    UniProtKB/TrEMBL
    D3Z7V3, F8WIH0
    Conserved Domains (3) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 757
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  3. XM_036158926.1 → XP_036014819.1  sarcolemmal membrane-associated protein isoform X15

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 757
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  4. XM_036158927.1 → XP_036014820.1  sarcolemmal membrane-associated protein isoform X16

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG1196
    Location:161 → 754
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  5. XM_036158933.1 → XP_036014826.1  sarcolemmal membrane-associated protein isoform X24

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG1196
    Location:161 → 733
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  6. XM_036158930.1 → XP_036014823.1  sarcolemmal membrane-associated protein isoform X19

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG1196
    Location:161 → 750
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  7. XM_036158931.1 → XP_036014824.1  sarcolemmal membrane-associated protein isoform X20

    Conserved Domains (3) summary
    COG1196
    Location:161 → 750
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  8. XM_036158924.1 → XP_036014817.1  sarcolemmal membrane-associated protein isoform X13

    Conserved Domains (3) summary
    COG1196
    Location:161 → 771
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  9. XM_006519725.2 → XP_006519788.1  sarcolemmal membrane-associated protein isoform X1

    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 812
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  10. XM_036158932.1 → XP_036014825.1  sarcolemmal membrane-associated protein isoform X22

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG1196
    Location:161 → 737
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  11. XM_006519727.3 → XP_006519790.1  sarcolemmal membrane-associated protein isoform X2

    UniProtKB/TrEMBL
    F8WIH0, H7BX64
    Related
    ENSMUSP00000087836.5, ENSMUST00000090359.11
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  12. XM_030248101.2 → XP_030103961.1  sarcolemmal membrane-associated protein isoform X25

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 732
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  13. XM_006519737.3 → XP_006519800.1  sarcolemmal membrane-associated protein isoform X27

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    COG0419
    Location:167 → 717
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

  14. XM_006519735.3 → XP_006519798.1  sarcolemmal membrane-associated protein isoform X21

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    COG1196
    Location:161 → 737
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

  15. XM_006519729.3 → XP_006519792.1  sarcolemmal membrane-associated protein isoform X7

    UniProtKB/TrEMBL
    F8WIH0
    Related
    ENSMUSP00000107950.3, ENSMUST00000112331.9
    Conserved Domains (2) summary
    COG1196
    Location:161 → 778
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

  16. XM_036158922.1 → XP_036014815.1  sarcolemmal membrane-associated protein isoform X8

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG1196
    Location:161 → 778
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  17. XM_017316229.3 → XP_017171718.1  sarcolemmal membrane-associated protein isoform X23

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 733
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  18. XM_036158934.1 → XP_036014827.1  sarcolemmal membrane-associated protein isoform X26

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    COG1196
    Location:161 → 733
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  19. XM_006519730.3 → XP_006519793.1  sarcolemmal membrane-associated protein isoform X10

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 774
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  20. XM_036158929.1 → XP_036014822.1  sarcolemmal membrane-associated protein isoform X18

    Conserved Domains (3) summary
    COG1196
    Location:161 → 754
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  21. XM_006519726.3 → XP_006519789.1  sarcolemmal membrane-associated protein isoform X3

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  22. XM_036158921.1 → XP_036014814.1  sarcolemmal membrane-associated protein isoform X5

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  23. XM_006519731.3 → XP_006519794.1  sarcolemmal membrane-associated protein isoform X9

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 774
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  24. XM_036158923.1 → XP_036014816.1  sarcolemmal membrane-associated protein isoform X11

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:156 → 774
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  25. XM_036158928.1 → XP_036014821.1  sarcolemmal membrane-associated protein isoform X17

    Conserved Domains (3) summary
    COG1196
    Location:161 → 754
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  26. XM_036158920.1 → XP_036014813.1  sarcolemmal membrane-associated protein isoform X4

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (3) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:156 → 795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd21911
    Location:163 → 225
    CC1_SLMAP; first coiled-coil (CC1) domain found in Sarcolemmal membrane-associated protein

  27. XM_006519728.3 → XP_006519791.1  sarcolemmal membrane-associated protein isoform X6

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR02168
    Location:163 → 791
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  28. XM_006519732.3 → XP_006519795.1  sarcolemmal membrane-associated protein isoform X12

    UniProtKB/TrEMBL
    F8WIH0
    Conserved Domains (2) summary
    COG1196
    Location:161 → 771
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00060
    Location:14 → 108
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

  29. XM_036158936.1 → XP_036014829.1  sarcolemmal membrane-associated protein isoform X30

    Conserved Domains (1) summary
    COG1196
    Location:67 → 335
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  30. XM_036158937.1 → XP_036014830.1  sarcolemmal membrane-associated protein isoform X31

    UniProtKB/TrEMBL
    F6UV57
    Conserved Domains (1) summary
    COG1196
    Location:67 → 335
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  31. XM_006519738.4 → XP_006519801.1  sarcolemmal membrane-associated protein isoform X29

    UniProtKB/TrEMBL
    F6YCM8
    Related
    ENSMUSP00000117276.2, ENSMUST00000145738.8
    Conserved Domains (1) summary
    TIGR02168
    Location:66 → 376
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3URD3.2 GenPept UniProtKB/Swiss-Prot:Q3URD3

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