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THM1 thioredoxin M-type 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839436, updated on 18-Sep-2024

Summary

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Official Symbol
THM1
Official Full Name
thioredoxin M-type 1
Primary source
TAIR:AT1G03680
Locus tag
AT1G03680
See related
Araport:AT1G03680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ABC transporter of the mitochondrion 1; ARABIDOPSIS THIOREDOXIN M-TYPE 1; ATHM1; ATM1; thioredoxin M-type 1; THIOREDOXIN M-TYPE 1; TRX-M1
Summary
encodes a chloroplast thioredoxin similar to prokaryotic thioredoxins.
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Genomic context

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See THM1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (916772..918064, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ankyrin-repeat containing protein Neighboring gene ncRNA Neighboring gene ankyrin repeat family protein Neighboring gene DTW domain-containing protein Neighboring gene Uncharacterized protein family (UPF0497)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Prompt and easy activation by specific thioredoxins of calvin cycle enzymes of Arabidopsis thaliana associated in the GAPDH/CP12/PRK supramolecular complex. Marri L, et al. Mol Plant, 2009 Mar. PMID 19825612
  2. M-type thioredoxins are involved in the xanthophyll cycle and proton motive force to alter NPQ under low-light conditions in Arabidopsis. Da Q, et al. Plant Cell Rep, 2018 Feb. PMID 29080907
  3. Evidence for a role of chloroplastic m-type thioredoxins in the biogenesis of photosystem II in Arabidopsis. Wang P, et al. Plant Physiol, 2013 Dec. PMID 24151299, Free PMC Article
  4. Redox regulation of chloroplastic glucose-6-phosphate dehydrogenase: a new role for f-type thioredoxin. Née G, et al. FEBS Lett, 2009 Sep 3. PMID 19631646
  5. Heterologous complementation of yeast reveals a new putative function for chloroplast m-type thioredoxin. Issakidis-Bourguet E, et al. Plant J, 2001 Jan. PMID 11169189

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that the m-type thioredoxins TRX-m1, TRX-m2, and TRX-m4 (TRX-ms) interact with the xanthophyll cycle enzyme zeaxanthin epoxidase (ZE) and are required for maintaining the redox-dependent stabilization of ZE.
    Title: M-type thioredoxins are involved in the xanthophyll cycle and proton motive force to alter NPQ under low-light conditions in Arabidopsis.
  2. These results suggest an important role for TRX m1, TRX m2, and TRX m4 proteins in the biogenesis of photosystem II.
    Title: Evidence for a role of chloroplastic m-type thioredoxins in the biogenesis of photosystem II in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_179254.7

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables enzyme activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables enzyme inhibitor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-disulfide reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables salicylic acid binding HDA PubMed 
Process Evidence Code Pubs
involved_in negative regulation of catalytic activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of catalytic activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast envelope HDA PubMed 
located_in chloroplast stroma HDA PubMed 
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
NOT located_in chloroplast thylakoid IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region HDA PubMed 
located_in stromule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in thylakoid HDA PubMed 

General protein information

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Preferred Names
thioredoxin M-type 1
NP_849585.1
  • thioredoxin M-type 1 (THM1); FUNCTIONS IN: enzyme activator activity; INVOLVED IN: response to oxidative stress, response to cold, positive regulation of catalytic activity; LOCATED IN: thylakoid, apoplast, stromule, chloroplast, chloroplast stroma; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin, core (InterPro:IPR015467), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin (InterPro:IPR005746), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT4G03520.1); Has 21675 Blast hits to 20380 proteins in 3008 species: Archae - 297; Bacteria - 11532; Metazoa - 2886; Fungi - 1120; Plants - 1860; Viruses - 8; Other Eukaryotes - 3972 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    916772..918064 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179254.7 → NP_849585.1  thioredoxin M-type 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849585.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O48737
    UniProtKB/TrEMBL
    A0A178W6J8, A0A5S9SFV5
    Conserved Domains (1) summary
    TIGR01068
    Location:79 → 179
    thioredoxin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O48737.1

Gene LinkOut

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