U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

bag6 BCL2 associated athanogene 6 [ Danio rerio (zebrafish) ]

Gene ID: 83910, updated on 12-Sep-2024

Summary

Official Symbol
bag6provided by ZNC
Official Full Name
BCL2 associated athanogene 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-010501-5
See related
Ensembl:ENSDARG00000075892 AllianceGenome:ZFIN:ZDB-GENE-010501-5
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
bat3; wu:fi30e10
Summary
Predicted to enable misfolded protein binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to act upstream of or within apoptotic process and chromatin organization. Predicted to be located in extracellular region and nucleus. Predicted to be part of BAT3 complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human BAG6 (BAG cochaperone 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See bag6 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (34618340..34658061, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (34760369..34800106, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene tetraspanin 13a Neighboring gene LINE-1 reverse transcriptase homolog Neighboring gene lymphotoxin alpha (TNF superfamily, member 1) Neighboring gene tumor necrosis factor b (TNF superfamily, member 2)

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of BAT3 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large proline-rich protein BAG6
Names
HLA-B-associated transcript 3
etID62210.15

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201288.1NP_958445.1  large proline-rich protein BAG6

    See identical proteins and their annotated locations for NP_958445.1

    Status: PROVISIONAL

    Source sequence(s)
    BC052476
    UniProtKB/TrEMBL
    Q7SZF4
    Related
    ENSDARP00000102380.1, ENSDART00000110964.3
    Conserved Domains (3) summary
    cd01809
    Location:979
    Scythe_N; Ubiquitin-like domain of Scythe protein
    smart00213
    Location:979
    UBQ; Ubiquitin homologues
    pfam12057
    Location:282400
    DUF3538; Domain of unknown function (DUF3538)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    34618340..34658061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157765.3XP_005157822.1  large proline-rich protein BAG6 isoform X1

    UniProtKB/TrEMBL
    A0A2R8QDI1, A0A8M2B4R7
    Related
    ENSDARP00000151719.1, ENSDART00000186605.1
    Conserved Domains (3) summary
    cd01809
    Location:979
    Scythe_N; Ubiquitin-like domain of Scythe protein
    smart00213
    Location:979
    UBQ; Ubiquitin homologues
    pfam12057
    Location:282400
    DUF3538; Domain of unknown function (DUF3538)