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UGT74B1 UDP-glucosyl transferase 74B1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839022, updated on 18-Sep-2024

Summary

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Official Symbol
UGT74B1
Official Full Name
UDP-glucosyl transferase 74B1
Primary source
TAIR:AT1G24100
Locus tag
AT1G24100
See related
Araport:AT1G24100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F3I6.2; F3I6_2; UDP-glucosyl transferase 74B1
Summary
Encodes a UDP-glucose:thiohydroximate S-glucosyltransferase, involved in glucosinolate biosynthesis
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Genomic context

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See UGT74B1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (8525334..8527087, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Putative thiol-disulfide oxidoreductase DCC Neighboring gene ncRNA Neighboring gene Peroxidase superfamily protein Neighboring gene ARG1-like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition. Kopycki J, et al. Biochem J, 2013 Feb 15. PMID 23150922
  2. Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. Grubb CD, et al. Plant J, 2004 Dec. PMID 15584955
  3. Glucosinolate metabolites required for an Arabidopsis innate immune response. Clay NK, et al. Science, 2009 Jan 2. PMID 19095898, Free PMC Article
  4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
  5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition.
    Title: Kinetic analysis of Arabidopsis glucosyltransferase UGT74B1 illustrates a general mechanism by which enzymes can escape product inhibition.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_102256.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables thiohydroximate beta-D-glucosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables thiohydroximate beta-D-glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within defense response by callose deposition in cell wall IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within glucosinolate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in nucleus HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
UDP-glucosyl transferase 74B1
NP_173820.1
  • UDP-glucosyl transferase 74B1 (UGT74B1); CONTAINS InterPro DOMAIN/s: UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-glycosyltransferase 74 F1 (TAIR:AT2G43840.1); Has 7754 Blast hits to 7677 proteins in 493 species: Archae - 0; Bacteria - 488; Metazoa - 2030; Fungi - 39; Plants - 5027; Viruses - 105; Other Eukaryotes - 65 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    8525334..8527087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102256.3 → NP_173820.1  UDP-glucosyl transferase 74B1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173820.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O48676, Q0WLE1, W8PVB1
    UniProtKB/TrEMBL
    A0A178WKT6, A0A5S9VTH6
    Conserved Domains (1) summary
    cl10013
    Location:7 → 455
    Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O48676.1

Gene LinkOut

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